Claudin 7 Antikörper (C-Term)

Produktnummer ABIN951552

Dieses Anti-Claudin 7-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von Claudin 7 in WB, IHC (p), FACS und EIA. Geeignet für Human.

Kurzübersicht für Claudin 7 Antikörper (C-Term) (ABIN951552)

Target: Claudin 7 (CLDN7)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Claudin 7 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS), Enzyme Immunoassay (EIA)

Produktdetails anti-Claudin 7 Antikörper

Bindungsspezifität: AA 179-209, C-Term

Spezifität: This antibody reacts to CLDN7.

Kreuzreaktivität (Details): Species reactivity (tested):Human.

Aufreinigung: Affinity chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide between 179-209 amino acids from the C-terminal region of human CLDN7

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS, 0.09 % (W/V) sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu Claudin 7

Target: Claudin 7 (CLDN7)

Andere Bezeichnung: Claudin-7 / CLDN7

Hintergrund: This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. Differential expression of this gene has been observed in different types of malignancies, including breast cancer, ovarian cancer, hepatocellular carcinomas, urinary tumors, prostate cancer, lung cancer, head and neck cancers, thyroid carcinomas, etc.. Alternatively spliced transcript variants encoding different isoforms have been found.Synonyms: CEPTRL2, CLDN-7, CPETRL2

Molekulargewicht: 22418 Da

Gen-ID: 1366

NCBI Accession: NP_001171951

Pathways: Hepatitis C