RUVBL1 Antikörper

Produktnummer ABIN932457

Dieses Anti-RUVBL1-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von RUVBL1 in WB, FACS, ICC und DB. Geeignet für Human.

Kurzübersicht für RUVBL1 Antikörper (ABIN932457)

Target: RUVBL1 (RuvB-Like 1 (E. Coli) (RUVBL1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser RUVBL1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS), Immunocytochemistry (ICC), Dot Blot (DB)

Klon: 2943C1a

Produktdetails anti-RUVBL1 Antikörper

Kreuzreaktivität: Human

Kreuzreaktivität (Details): Other species not studied.

Aufreinigung: Protein G affinity chromatography

Immunogen: RUVBL1 antibody was raised in mouse using recombinant Human Ruvb-Like 1 (E. Coli) (Ruvbl1)

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise: WB: 0.2-2 µg/mL, FC: 0.5-2 µg/sample, ICC: 2-100 µg/mL
Optimal conditions should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: Lot specific

Buffer: RUVBL1 antibody in PBS (3.0 mM KCl, 1.5 mM KH2 PO4 , 140 mM NaCl, 8.0 mM Na2 HPO4 (pH 7.4)) containing 1 % bovine serum albumin (BSA) and 0.05 % sodium azide (NaN3 ).

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handhabung: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 2-8 °C for up to one year. We recommend long term storage at -20 °C.

Details zu RUVBL1

Target: RUVBL1 (RuvB-Like 1 (E. Coli) (RUVBL1))

Andere Bezeichnung: RUVBL1

Hintergrund: This gene possesses single-stranded DNA-stimulated ATPase and ATP-dependent DNA helicase (3' to 5') activity. Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histone H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. Synonyms: Monoclonal RUVBL1 antibody, Anti-RUVBL1 antibody, RuvB (E coli homolog)-like 1 antibody, RVB1 antibody, ECP54 antibody, TIP49 antibody, NMP238 antibody, TIP49A antibody.

Pathways: Telomere Maintenance