CCDC42 Antikörper (AA 221-312) (Alexa Fluor 555)

Produktnummer ABIN887729

Produktdetails anti-CCDC42 Antikörper

Target: CCDC42 (Coiled-Coil Domain Containing 42 (CCDC42))

Bindungsspezifität: AA 221-312

Reaktivität: Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CCDC42 Antikörper ist konjugiert mit Alexa Fluor 555

Applikation: Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))

Homologie: Human,Dog,Cow,Sheep,Pig,Horse,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CCDC42

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C/-80 °C

Informationen zur Lagerung: Store at -20°C, for long storage, store at -80°C. Avoid multiple freeze-thaw cycles

Haltbarkeit: 12 months

Details zu CCDC42

Target: CCDC42 (Coiled-Coil Domain Containing 42 (CCDC42))

Andere Bezeichnung: CCDC42 (CCDC42 Produkte)

Synonyme: RGD1565925 antikoerper, CCDC42A antikoerper, A530001H01Rik antikoerper, coiled-coil domain containing 42 antikoerper, Ccdc42 antikoerper, CCDC42 antikoerper

Hintergrund:

The coiled-coil domain is a structural motif found in proteins that are involved in a diverse array of biological functions such as the regulation of gene expression, cell division, membrane fusion and drug extrusion and delivery. CCDC42 (coiled-coil domain containing 42) is a 316 amino acid protein encoded by a gene that maps to human chromosome 17p13.1. Encoding over 1,200 genes, chromosome 17 comprises over 2.5 % of the human genome. Two key tumor suppressor genes are associated with chromosome 17, namely, p53 and BRCA1. Tumor suppressor p53 is necessary for maintenance of cellular genetic integrity by moderating cell fate through DNA repair versus cell death. Malfunction or loss of p53 expression is associated with malignant cell growth and Li-Fraumeni syndrome.

Subcellular location: Cytoplasm, Nucleus

Synonyms: CCDC42A, Coiled coil domain containing 42, Coiled coil domain containing protein 42A, FLJ32734, OTTMUSP00000006142, RGD1565925, RP23-400O5.1, CCD42_HUMAN.

Gen-ID: 146849