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Rekombinanter T Cell Receptor Antikörper

Reaktivität: Maus FACS, IP, Crys, IF Wirt: Kaninchen Chimeric Desire-1 unconjugated Recombinant Antibody
Produktnummer ABIN7072447
  • Target
    T Cell Receptor
    Antikörpertyp
    Recombinant Antibody
    Reaktivität
    • 6
    • 5
    Maus
    Wirt
    • 4
    • 3
    • 2
    • 2
    Kaninchen
    Klonalität
    • 9
    • 2
    Chimeric
    Konjugat
    • 10
    • 1
    Unkonjugiert
    Applikation
    • 11
    • 7
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    Flow Cytometry (FACS), Immunoprecipitation (IP), Crystallization (Crys), Immunofluorescence (IF)
    Verwendungszweck
    Anti-TCR [Desire-1], Rabbit IgG, kappa
    Spezifität
    MAb desire-1 recognises an epitope contributed by both the alpha and beta chains of the KB5-C20 TCR.
    Produktmerkmale

    Original Species of Ab: Mouse

    Original Format of Ab: IgG

    Aufreinigung
    Protein A affinity purified
    Immunogen
    mAb desire-1 was obtained after fusion of spleen cells from a BALB.K mouse immunised twice with KB5-C20 clone cells in RPMI 1640 medium, with non-Ig-producing myeloma cells X63-Ag8.653. Desire-1 was selected for its capacity to inhibit selectively the H-2Kb-specific cytolysis by clone KB5-C20.
    Klon
    Desire-1
    Isotyp
    IgG kappa
  • Applikationshinweise
    Desire-1 has been used for the immunoprecipitation of soluble TCR molecules (Gregoire 1991 & Hua 1986). An FITC conjugated desire-1 has been used in flow cytometric analysis as a marker for clonotype expression (Schonrich 1991). Further, a Fab fragment derived from desire-1 has been used in the crystallisation of the T-cell receptor for 3D structure determination (Housset 1997).
    Kommentare

    This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG format, for improved compatibility with existing reagents, assays and techniques.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    1 mg/mL
    Buffer
    PBS with 0.02 % Proclin 300.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
  • Target
    T Cell Receptor
    Andere Bezeichnung
    TCR
    Hintergrund
    T cell receptor, T-cell receptor, Ti
    UniProt
    P01852, P01849
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