Dynamin 1-Like (DNM1L) Antikörper

Details zu Produkt Nr. ABIN6569298
Target
Reaktivität
Human, Maus
82
55
52
5
3
3
3
2
2
2
1
1
1
1
1
1
1
1
Wirt
Kaninchen
75
8
Klonalität
Polyklonal
Konjugat
Unkonjugiert
7
5
5
5
5
4
4
3
2
2
1
1
1
1
Applikation
Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blotting (WB)
45
33
28
17
13
10
10
6
5
3
1
Optionen
Immunogen Recombinant protein of human DNM1L
Isotyp IgG
Reinigung Affinity purification
Target
Andere Bezeichnung DRP1 (DNM1L Antibody Abstract)
Hintergrund

Synonyms: DLP1,dnm1l,DNM1L,Dnm1p/Vps1p-like protein,dnml1,DRP1,DVLP,Dymple,Dynamin 1 like,Dynamin family member proline-rich carboxyl-terminal domain less,Dynamin like protein,Dynamin related protein 1,Dynamin-1-like protein,Dynamin-like protein 4,Dynamin-like protein,Dynamin-like protein IV,Dynamin-related protein 1,DYNIV 11,EMPF,EMPF1,FLJ41912,HdynIV,VPS1

Background: This gene encodes a member of the dynamin superfamily of GTPases. The encoded protein mediates mitochondrial and peroxisomal division, and is involved in developmentally regulated apoptosis and programmed necrosis. Dysfunction of this gene is implicated in several neurological disorders, including Alzheimer's disease. Mutations in this gene are associated with the autosomal dominant disorder, encephalopathy, lethal, due to defective mitochondrial and peroxisomal fission (EMPF). Alternative splicing results in multiple transcript variants encoding different isoforms.
Molekulargewicht

Observed_MW: 78-82kDa

Calculated_MW: 60kDa/78kDa/79kDa/80kDa/81kDa/82kDa/83kDa
Gen-ID 10059
UniProt O00429
Applikations-hinweise WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200
Beschränkungen Nur für Forschungszwecke einsetzbar
Konzentration 1 mg/mL
Buffer Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20°C. Avoid freeze / thaw cycles.
Bilder
Image no. 1 for anti-Dynamin 1-Like (DNM1L) antibody (ABIN6569298) Immunohistochemistry of paraffin-embedded human liver injury using DNM1L antibody.
Image no. 2 for anti-Dynamin 1-Like (DNM1L) antibody (ABIN6569298) Western blot analysis of extracts of various cell lines, using DNM1L antibody.
Image no. 3 for anti-Dynamin 1-Like (DNM1L) antibody (ABIN6569298) Immunofluorescence analysis of HeLa cells using DNM1L antibody.