Synonyms: Bifunctional epoxide hydrolase 2,CEH,Cytosolic epoxide hydrolase,EPHX2,Epoxide hydratase,Epoxide hydrolase 2,Epoxide hydrolase 2 cytoplasmic,epoxide hydrolase 2, cytosolic,Epoxide hydrolase soluble,HYES,SEH,Soluble epoxide hydrolase
Background: This gene encodes a member of the epoxide hydrolase family. The protein, found in both the cytosol and peroxisomes, binds to specific epoxides and converts them to the corresponding dihydrodiols. Mutations in this gene have been associated with familial hypercholesterolemia. Alternatively spliced transcript variants have been described.