SLC22A5 Antikörper (Solute Carrier Family 22 Member 5)

Details for Product anti-SLC22A5 Antibody No. ABIN6568843
Target
Reaktivität
Human, Maus
22
17
15
3
3
2
2
2
1
1
Wirt
Kaninchen
23
Klonalität
Polyklonal
Konjugat
Dieser SLC22A5 Antikörper ist unkonjugiert
1
1
1
1
1
1
1
Applikation
Immunofluorescence (IF), Western Blotting (WB)
18
9
4
3
1
1
1
1
Optionen
Immunogen Recombinant protein of human SLC22A5
Isotyp IgG
Reinigung Affinity purification
Target
Andere Bezeichnung SLC22A5 (SLC22A5 Antibody Abstract)
Hintergrund

Synonyms: CDSP,High-affinity sodium-dependent carnitine cotransporter,OCTN2,OCTN2VT,Organic cation/carnitine transporter 2,S22A5,Slc22a5,Solute carrier family 22 (organic cation/carnitine transporter) member 5,Solute carrier family 22 member 5

Background: Polyspecific organic cation transporters in the liver, kidney, intestine, and other organs are critical for elimination of many endogenous small organic cations as well as a wide array of drugs and environmental toxins. The encoded protein is a plasma integral membrane protein which functions both as an organic cation transporter and as a sodium-dependent high affinity carnitine transporter. The encoded protein is involved in the active cellular uptake of carnitine. Mutations in this gene are the cause of systemic primary carnitine deficiency (CDSP), an autosomal recessive disorder manifested early in life by hypoketotic hypoglycemia and acute metabolic decompensation, and later in life by skeletal myopathy or cardiomyopathy. Alternative splicing of this gene results in multiple transcript variants.

Molekulargewicht

Observed_MW: 70kDa

Calculated_MW: 24kDa/62kDa/65kDa

Gen-ID 6584
UniProt O76082
Applikations-hinweise WB 1:500 - 1:2000 IF 1:50 - 1:200
Beschränkungen Nur für Forschungszwecke einsetzbar
Konzentration 1 mg/mL
Buffer Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20°C. Avoid freeze / thaw cycles.
Bilder
Image no. 1 for anti-Solute Carrier Family 22 Member 5 (SLC22A5) antibody (ABIN6568843) Western blot analysis of extracts of various cell lines, using SLC22A5 antibody.
Image no. 2 for anti-Solute Carrier Family 22 Member 5 (SLC22A5) antibody (ABIN6568843) Immunofluorescence analysis of MCF-7 cells using SLC22A5 antibody.