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CYBB Antikörper

CYBB Reaktivität: Human, Maus, Ratte WB, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN5964622
  • Target Alle CYBB Antikörper anzeigen
    CYBB (Cytochrome B-245, beta Polypeptide (CYBB))
    Reaktivität
    • 63
    • 43
    • 43
    • 19
    • 16
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 55
    • 7
    • 2
    Kaninchen
    Klonalität
    • 49
    • 15
    Polyklonal
    Konjugat
    • 29
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CYBB Antikörper ist unkonjugiert
    Applikation
    • 42
    • 19
    • 18
    • 13
    • 13
    • 9
    • 9
    • 6
    • 5
    • 2
    • 2
    Western Blotting (WB), Immunohistochemistry (IHC)
    Aufreinigung
    Affinity purification
    Immunogen
    A synthetic peptide of human CYBB
    Isotyp
    IgG
    Top Product
    Discover our top product CYBB Primärantikörper
  • Applikationshinweise
    WB 1:500 - 1:2000 IHC 1:50 - 1:200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    1 mg/mL
    Buffer
    Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    CYBB (Cytochrome B-245, beta Polypeptide (CYBB))
    Andere Bezeichnung
    CYBB (CYBB Produkte)
    Hintergrund

    Synonyms: AMCBX2,CGD,CGD91-phox,CY24B,CYBB,Cytochrome b 245,beta polypeptide,Cytochrome b(558) beta chain,Cytochrome b(558) subunit beta,Cytochrome b-245 heavy chain,Cytochrome b558 subunit beta,GP91 PHOX,gp91-1,gp91-phox,GP91PHOX,Heme-binding membrane glycoprotein gp91phox,NADPH oxidase 2,Neutrophil cytochrome b 91 kDa polypeptide,NOX2,p22 phagocyte B-cytochrome,P91 PHOX,p91-PHOX,Superoxide-generating NADPH oxidase heavy chain subunit

    Background: Cytochrome b (-245) is composed of cytochrome b alpha (CYBA) and beta (CYBB) chain. It has been proposed as a primary component of the microbicidal oxidase system of phagocytes. CYBB deficiency is one of five described biochemical defects associated with chronic granulomatous disease (CGD). In this disorder, there is decreased activity of phagocyte NADPH oxidase, neutrophils are able to phagocytize bacteria but cannot kill them in the phagocytic vacuoles. The cause of the killing defect is an inability to increase the cell's respiration and consequent failure to deliver activated oxygen into the phagocytic vacuole.

    Molekulargewicht

    Observed_MW: 65kDa

    Calculated_MW: 65kDa

    Gen-ID
    1536
    UniProt
    P04839
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