Synonyms: C2H2 like zinc finger protein ,C2H2 like zinc finger protein rearranged in thyroid adenomas,C2H2-like zinc finger protein rearranged in thyroid adenomas,DKFZp686L0787,KRAB zinc finger protein,OTTHUMP00000223038,OTTHUMP00000223039,OTTHUMP00000223040,OTTHUMP00000223041,OTTHUMP00000223042,OTTHUMP00000223043,OTTHUMP00000223045,OTTHUMP00000223046,OTTHUMP00000223047,OTTHUMP00000223048,OTTHUMP00000223052,OTTHUMP00000223053,OTTHUMP00000223054,RITA ,Zinc finger protein 331,Zinc finger protein 361,Zinc finger protein 463,ZN331,ZNF331,ZNF361 ,ZNF463
Background: This gene encodes a zinc finger protein containing a KRAB (Kruppel-associated box) domain found in transcriptional repressors. This gene may be methylated and silenced in cancer cells. This gene is located within a differentially methylated region (DMR) and shows allele-specific expression in placenta. Alternative splicing and the use of alternative promoters results in multiple transcript variants encoding the same protein.