Synonyms: FP,MGC120498,MGC46203,PF2R,PGF receptor,PGF2 alpha receptor ,PGF2-alpha receptor,Prostaglandin F receptor ,Prostaglandin F2-alpha receptor,Prostaglandin receptor 2 alpha,Prostanoid FP receptor,PTGFR
Background: The protein encoded by this gene is member of the G-protein coupled receptor family. This protein is a receptor for prostaglandin F2-alpha (PGF2-alpha), which is known to be a potent luteolytic agent, and may also be involved in modulating intraocular pressure and smooth muscle contraction in uterus. Knockout studies in mice suggest that the interaction of PGF2-alpha with this receptor may initiate parturition in ovarian luteal cells and thus induce luteolysis. Two transcript variants encoding different isoforms have been found for this gene.