Synonyms: A kinase (PRKA) anchor protein 4,A kinase anchor protein 4,A kinase anchor protein 82 kDa,A-kinase anchor protein 4,A-kinase anchor protein 82 kDa,AKAP 4,AKAP 82,AKAP-4,AKAP4,AKAP4,AKAP82,FSC 1,FSC1,hAKAP 82,hAKAP82,HI,Major sperm fibrous sheath protein,p82,PRKA 4,PRKA4,Protein kinase A anchoring protein 4,Protein kinase A-anchoring protein 4,Testis specific gene HI
Background: The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein is localized to the sperm flagellum and may be involved in the regulation of sperm motility. Alternative splicing of this gene results in two transcript variants encoding different isoforms.