ABCB7 Antikörper

Produktnummer ABIN6568439

Produktdetails anti-ABCB7 Antikörper

Target: ABCB7 (ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 7 (ABCB7))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ABCB7 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), Immunofluorescence (IF)

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein of human ABCB7 (NP_004290.2).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC 1:50-1:200 IF 1:50-1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu ABCB7

Target: ABCB7 (ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 7 (ABCB7))

Andere Bezeichnung: ABCB7 (ABCB7 Produkte)

Synonyme: CG7955 antikoerper, Dmel\\CG7955 antikoerper, dABCB7 antikoerper, GB11034 antikoerper, ABCB7 antikoerper, fc20c02 antikoerper, wu:fc20c02 antikoerper, ABC7 antikoerper, ASAT antikoerper, Atm1p antikoerper, EST140535 antikoerper, AA517758 antikoerper, AU019072 antikoerper, Abc7 antikoerper, ATP binding cassette subfamily B member 7 antikoerper, ATP-binding cassette sub-family B member 7, mitochondrial antikoerper, ATP-binding cassette, sub-family B (MDR/TAP), member 7 antikoerper, ATP-binding cassette sub-family B member 7, mitochondrial-like antikoerper, ABCB7 antikoerper, LOC412749 antikoerper, abcb7 antikoerper, LOC100367778 antikoerper, LOC100467128 antikoerper, Abcb7 antikoerper

Hintergrund: The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. This gene encodes a half-transporter involved in the transport of heme from the mitochondria to the cytosol. With iron/sulfur cluster precursors as its substrates, this protein may play a role in metal homeostasis. Mutations in this gene have been associated with mitochondrial iron accumulation and isodicentric (X)(q13) and sideroblastic anemia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Molekulargewicht:

Observed_MW: 83kDa

Calculated_MW: 78kDa/82kDa

Gen-ID: 22

UniProt: O75027

Pathways: Transition Metal Ion Homeostasis