Synonyms: EAA 1,EAA1,Excitatory amino acid receptor 1,GluK4,Glutamate receptor,Glutamate receptor ionotropic kainate 4,Glutamate receptor ionotropic kainate 4 precursor,Glutamate receptor KA 1,Glutamate receptor KA 1precursor,Glutamate receptor KA-1,Glutamate receptor KA1,Glutamate receptor, ionotropic kainate 4,GRIK 4,GRIK,Grik4,GRIK4,ionotropic kainate 4,KA 1,KA1,OTTHUMP00000045951,OTTHUMP00000231881
Background: This gene encodes a protein that belongs to the glutamate-gated ionic channel family. Glutamate functions as the major excitatory neurotransmitter in the central nervous system through activation of ligand-gated ion channels and G protein-coupled membrane receptors. The protein encoded by this gene forms functional heteromeric kainate-preferring ionic channels with the subunits encoded by related gene family members. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.