IRF8 Antikörper (Interferon Regulatory Factor 8)

Details for Product anti-IRF8 Antibody No. ABIN6568119
Target
Reaktivität
Human
51
24
15
5
5
4
4
4
3
2
2
2
1
1
1
Wirt
Kaninchen
49
7
2
Klonalität
Polyklonal
Konjugat
Dieser IRF8 Antikörper ist unkonjugiert
3
2
2
1
1
1
1
1
1
1
1
1
Applikation
Immunofluorescence (IF), Western Blotting (WB)
47
25
14
6
4
4
4
2
2
1
1
1
1
Optionen
Immunogen Recombinant protein of human IRF8
Isotyp IgG
Reinigung Affinity purification
Target
Andere Bezeichnung IRF8 (IRF8 Antibody Abstract)
Hintergrund

Synonyms: H ICSBP,H-ICSBP,HGNC:5358,HICSBP,ICSBP 1,ICSBP,ICSBP1,Interferon consensus sequence binding protein 1,Interferon consensus sequence binding protein,Interferon consensus sequence-binding protein,Interferon regulatory factor 8,IRF 8,IRF-8,Irf8,IRF8,MYLS

Background: Interferon consensus sequence-binding protein (ICSBP) is a transcription factor of the interferon (IFN) regulatory factor (IRF) family. Proteins of this family are composed of a conserved DNA-binding domain in the N-terminal region and a divergent C-terminal region that serves as the regulatory domain. The IRF family proteins bind to the IFN-stimulated response element (ISRE) and regulate expression of genes stimulated by type I IFNs, namely IFN-alpha and IFN-beta. IRF family proteins also control expression of IFN-alpha and IFN-beta-regulated genes that are induced by viral infection.

Molekulargewicht

Observed_MW: 54kDa

Calculated_MW: 48kDa

Gen-ID 3394
UniProt Q02556
Pathways Cellular Response to Molecule of Bacterial Origin
Applikations-hinweise WB 1:500 - 1:2000 IF 1:50 - 1:200
Beschränkungen Nur für Forschungszwecke einsetzbar
Konzentration 1 mg/mL
Buffer Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20°C. Avoid freeze / thaw cycles.
Bilder
Image no. 1 for anti-Interferon Regulatory Factor 8 (IRF8) antibody (ABIN6568119) Western blot analysis of extracts of THP-1 cells, using IRF8 antibody.
Image no. 2 for anti-Interferon Regulatory Factor 8 (IRF8) antibody (ABIN6568119) Immunofluorescence analysis of A549 cells using IRF8 antibody.