Synonyms: A3G,ABC3G,APOBEC related cytidine deaminase,APOBEC related protein,APOBEC-related cytidine deaminase,APOBEC-related protein 9,APOBEC-related protein,APOBEC3G,Apolipoprotein B editing enzyme catalytic polypeptide like 3G,Apolipoprotein B mRNA editing enzyme catalytic polypeptide 3G,Apolipoprotein B mRNA editing enzyme catalytic polypeptide like 3G,Apolipoprotein B mRNA editing enzyme catalytic subunit 3G,apolipoprotein B mRNA editing enzyme cytidine deaminase,apolipoprotein B mRNA editing enzyme,catalytic polypeptide-like,ARCD,ARP-9,ARP9,bK150C2.7,CEM-15,CEM15,deoxycytidine deaminase,dJ494G10.1,DNA dC dU editing enzyme APOBEC 3G,DNA dC->dU editing enzyme,DNA dC->dU-editing enzyme APOBEC-3G,EC 3.5.4.,FLJ12740,MDS019,OTTHUMP00000028911,phorbolin-like protein,phorbolin-like protein MDS019
Background: This gene is a member of the cytidine deaminase gene family. It is one of seven related genes or pseudogenes found in a cluster, thought to result from gene duplication, on chromosome 22. Members of the cluster encode proteins that are structurally and functionally related to the C to U RNA-editing cytidine deaminase APOBEC1. The protein encoded by this gene catalyzes site-specific deamination of both RNA and single-stranded DNA. The encoded protein has been found to be a specific inhibitor of human immunodeficiency virus-1 (HIV-1) infectivity.