Synovial Sarcoma, X Breakpoint 2 (SSX2) Antikörper

Details zu Produkt Nr. ABIN6568037
Target
Reaktivität
Human, Maus, Ratte
48
3
2
Wirt
Kaninchen
42
6
Klonalität
Polyklonal
Konjugat
Unkonjugiert
3
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
Applikation
Immunofluorescence (IF)
28
13
10
7
6
6
4
1
1
Optionen
Immunogen Recombinant protein of human SSX2
Isotyp IgG
Reinigung Affinity purification
Target
Andere Bezeichnung SSX2 (SSX2 Antibody Abstract)
Hintergrund

Synonyms: Cancer/testis antigen 5.2,Cancer/testis antigen family 5,member 2a,Cancer/testis antigen family 5,member 2b,CT5.2,CT5.2A,CT5.2b,HD21,hom mel 40,HOM-MEL-40,MGC119055,MGC15364,MGC3884,Protein SSX2,RP11-552J9.2,sarcoma,synovial,X-chromosome related 2,SSx,SSX2,SSX2-SYT fusion gene,included,SSX2,SSX2B,Synovial sarcoma,synovial sarcoma X breakpoint 2,Synovial sarcoma,X breakpoint 2B,Tumor antigen HOM-MEL-40,X breakpoint 2

Background: The product of this gene belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneous humoral and cellular immune responses in cancer patients, and are potentially useful targets in cancer vaccine-based immunotherapy. This gene, and also the SSX1 and SSX4 family members, have been involved in t(X,18)(p11.2,q11.2) translocations that are characteristically found in all synovial sarcomas. This translocation results in the fusion of the synovial sarcoma translocation gene on chromosome 18 to one of the SSX genes on chromosome X. The encoded hybrid proteins are likely responsible for transforming activity. Alternative splicing of this gene results in multiple transcript variants. This gene also has an identical duplicate, GeneID: 727837, located about 45 kb downstream in the opposite orientation on chromosome X.

Molekulargewicht

Observed_MW: Refer to figures

Calculated_MW: 21kDa/25kDa

Gen-ID 6757
UniProt Q16385
Applikations-hinweise IF 1:50 - 1:200
Beschränkungen Nur für Forschungszwecke einsetzbar
Konzentration 1 mg/mL
Buffer Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20°C. Avoid freeze / thaw cycles.
Bilder
Image no. 1 for anti-Synovial Sarcoma, X Breakpoint 2 (SSX2) antibody (ABIN6568037) Immunofluorescence analysis of HeLa cells using SSX2 antibody.