TBL1XR1 Antikörper
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- Target Alle TBL1XR1 Antikörper anzeigen
- TBL1XR1 (Transducin (Beta)-Like 1 X-Linked Receptor 1 (TBL1XR1))
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Reaktivität
- Human, Maus
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser TBL1XR1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunofluorescence (IF)
- Aufreinigung
- Affinity purification
- Immunogen
- Recombinant protein of human TBL1XR1
- Isotyp
- IgG
- Top Product
- Discover our top product TBL1XR1 Primärantikörper
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- Applikationshinweise
- WB 1:500 - 1:2000 IF 1:50 - 1:200
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 1 mg/mL
- Buffer
- Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- TBL1XR1 (Transducin (Beta)-Like 1 X-Linked Receptor 1 (TBL1XR1))
- Andere Bezeichnung
- TBL1XR1 (TBL1XR1 Produkte)
- Hintergrund
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Synonyms: C21,DC42,F box like/WD repeat containing protein TBL1XR1,F-box-like/WD repeat-containing protein TBL1XR1,FLJ12894,IRA1,Nuclear receptor corepressor/HDAC3 complex subunit,Nuclear receptor corepressor/HDAC3 complex subunit TBLR1,TBL1 related protein 1,TBL1-related protein 1,TBL1R,TBL1XR1,Transducin (beta) like 1 X linked receptor 1,Transducin beta like 1X related protein 1,Transducin beta-like 1X-related protein 1
Background: This gene is a member of the WD40 repeat-containing gene family and shares sequence similarity with transducin (beta)-like 1X-linked (TBL1X). The protein encoded by this gene is thought to be a component of both nuclear receptor corepressor (N-CoR) and histone deacetylase 3 (HDAC 3) complexes, and is required for transcriptional activation by a variety of transcription factors. Mutations in these gene have been associated with some autism spectrum disorders, and one finding suggests that haploinsufficiency of this gene may be a cause of intellectual disability with dysmorphism. Mutations in this gene as well as recurrent translocations involving this gene have also been observed in some tumors.
- Molekulargewicht
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Observed_MW: 55-70kDa
Calculated_MW: 55kDa
- Gen-ID
- 79718
- UniProt
- Q9BZK7
- Pathways
- Regulation of Lipid Metabolism by PPARalpha
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