TBL1XR1 Antikörper (Transducin (Beta)-Like 1 X-Linked Receptor 1)

Details for Product anti-TBL1XR1 Antibody No. ABIN6567965
Target
Reaktivität
Human, Maus
71
34
23
5
5
5
5
4
2
2
2
1
1
1
1
1
Wirt
Kaninchen
54
17
Klonalität
Polyklonal
Konjugat
Dieser TBL1XR1 Antikörper ist unkonjugiert
4
3
3
2
2
2
2
2
2
2
2
2
1
1
1
1
1
Applikation
Immunofluorescence (IF), Western Blotting (WB)
54
25
19
13
11
11
10
3
1
1
1
1
1
Optionen
Immunogen Recombinant protein of human TBL1XR1
Isotyp IgG
Reinigung Affinity purification
Target
Andere Bezeichnung TBL1XR1 (TBL1XR1 Antibody Abstract)
Hintergrund

Synonyms: C21,DC42,F box like/WD repeat containing protein TBL1XR1,F-box-like/WD repeat-containing protein TBL1XR1,FLJ12894,IRA1,Nuclear receptor corepressor/HDAC3 complex subunit,Nuclear receptor corepressor/HDAC3 complex subunit TBLR1,TBL1 related protein 1,TBL1-related protein 1,TBL1R,TBL1XR1,Transducin (beta) like 1 X linked receptor 1,Transducin beta like 1X related protein 1,Transducin beta-like 1X-related protein 1

Background: This gene is a member of the WD40 repeat-containing gene family and shares sequence similarity with transducin (beta)-like 1X-linked (TBL1X). The protein encoded by this gene is thought to be a component of both nuclear receptor corepressor (N-CoR) and histone deacetylase 3 (HDAC 3) complexes, and is required for transcriptional activation by a variety of transcription factors. Mutations in these gene have been associated with some autism spectrum disorders, and one finding suggests that haploinsufficiency of this gene may be a cause of intellectual disability with dysmorphism. Mutations in this gene as well as recurrent translocations involving this gene have also been observed in some tumors.

Molekulargewicht

Observed_MW: 55-70kDa

Calculated_MW: 55kDa

Gen-ID 79718
UniProt Q9BZK7
Pathways Regulation of Lipid Metabolism by PPARalpha
Applikations-hinweise WB 1:500 - 1:2000 IF 1:50 - 1:200
Beschränkungen Nur für Forschungszwecke einsetzbar
Konzentration 1 mg/mL
Buffer Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20°C. Avoid freeze / thaw cycles.
Bilder
Image no. 1 for anti-Transducin (Beta)-Like 1 X-Linked Receptor 1 (TBL1XR1) antibody (ABIN6567965) Western blot analysis of extracts of various cell lines, using TBL1XR1 antibody.
Image no. 2 for anti-Transducin (Beta)-Like 1 X-Linked Receptor 1 (TBL1XR1) antibody (ABIN6567965) Immunofluorescence analysis of A549 cells using TBL1XR1 antibody.