XRCC6 Binding Protein 1 (XRCC6BP1) Antikörper

Details zu Produkt Nr. ABIN6567675
Target
Reaktivität
Maus, Ratte
9
1
1
1
1
1
1
1
1
Wirt
Kaninchen
5
4
Klonalität
Polyklonal
Applikation
Western Blotting (WB)
7
2
1
Optionen
Immunogen Recombinant protein of human ATP23
Isotyp IgG
Reinigung Affinity purification
Target
Andere Bezeichnung ATP23
Hintergrund

Synonyms: EC 3.4.24 ,Ku70 binding protein 3,KUB3,MGC134817,MGC134818,Mitochondrial inner membrane protease ATP23 homolog,XRCC6 binding protein 1

Background: The protein encoded by this gene is amplified in glioblastomas and interacts with the DNA binding subunit of DNA-dependent protein kinase. This kinase is involved in double-strand break repair (DSB), and higher expression of the encoded protein increases the efficiency of DSB. In addition, comparison to orthologous proteins strongly suggests that this protein is a metalloprotease important in the biosynthesis of mitochondrial ATPase. Several transcript variants encoding different isoforms have been found for this gene.

Molekulargewicht

Observed_MW: 28kDa

Calculated_MW: 28kDa

Gen-ID 91419
UniProt Q9Y6H3
Applikations-hinweise WB 1:1000 - 1:3000
Beschränkungen Nur für Forschungszwecke einsetzbar
Konzentration 1 mg/mL
Buffer Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20°C. Avoid freeze / thaw cycles.
Bilder
Image no. 1 for anti-XRCC6 Binding Protein 1 (XRCC6BP1) antibody (ABIN6567675) Western blot analysis of extracts of various cell lines, using ATP23 antibody.