SNX13 Antikörper (Sorting Nexin 13)

Details for Product anti-SNX13 Antibody No. ABIN6567653
Target
Reaktivität
Human
22
Wirt
Kaninchen
19
3
Klonalität
Polyklonal
Konjugat
Dieser SNX13 Antikörper ist unkonjugiert
2
2
2
2
2
2
Applikation
Western Blotting (WB)
22
15
2
2
1
1
1
1
Optionen
Immunogen Recombinant protein of human SNX13
Isotyp IgG
Reinigung Affinity purification
Target
Andere Bezeichnung SNX13 (SNX13 Antibody Abstract)
Hintergrund

Synonyms: KIAA0713,RGS domain and PHOX domain containing protein,RGS PX1,Sorting nexin 13

Background: This gene encodes a PHOX domain- and RGS domain-containing protein that belongs to the sorting nexin (SNX) family and the regulator of G protein signaling (RGS) family. The PHOX domain is a phosphoinositide binding domain, and the SNX family members are involved in intracellular trafficking. The RGS family members are regulatory molecules that act as GTPase activating proteins for G alpha subunits of heterotrimeric G proteins. The RGS domain of this protein interacts with G alpha(s), accelerates its GTP hydrolysis, and attenuates G alpha(s)-mediated signaling. Overexpression of this protein delayes lysosomal degradation of the epidermal growth factor receptor. Because of its bifunctional role, this protein may link heterotrimeric G protein signaling and vesicular trafficking.

Molekulargewicht

Observed_MW: 112kDa

Calculated_MW: 110kDa/112kDa

Gen-ID 23161
UniProt Q9Y5W8
Pathways Regulation of G-Protein Coupled Receptor Protein Signaling
Applikations-hinweise WB 1:500 - 1:2000
Beschränkungen Nur für Forschungszwecke einsetzbar
Konzentration 1 mg/mL
Buffer Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20°C. Avoid freeze / thaw cycles.
Bilder
Image no. 1 for anti-Sorting Nexin 13 (SNX13) antibody (ABIN6567653) Western blot analysis of extracts of various cell lines, using SNX13 antibody.