SNX13 Antikörper

Produktnummer ABIN6567653

Produktdetails anti-SNX13 Antikörper

Target: SNX13 (Sorting Nexin 13 (SNX13))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SNX13 Antikörper ist unkonjugiert

Applikation: Immunofluorescence (IF)

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein of human SNX13 (NP_055947.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF 1:50-1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu SNX13

Target: SNX13 (Sorting Nexin 13 (SNX13))

Andere Bezeichnung: SNX13 (SNX13 Produkte)

Synonyme: MGC142644 antikoerper, DKFZp469H181 antikoerper, Rgs-px1 antikoerper, mKIAA0713 antikoerper, RGS-PX1 antikoerper, sorting nexin 13 antikoerper, SNX13 antikoerper, Snx13 antikoerper

Hintergrund: This gene encodes a PHOX domain- and RGS domain-containing protein that belongs to the sorting nexin (SNX) family and the regulator of G protein signaling (RGS) family. The PHOX domain is a phosphoinositide binding domain, and the SNX family members are involved in intracellular trafficking. The RGS family members are regulatory molecules that act as GTPase activating proteins for G alpha subunits of heterotrimeric G proteins. The RGS domain of this protein interacts with G alpha(s), accelerates its GTP hydrolysis, and attenuates G alpha(s)-mediated signaling. Overexpression of this protein delayes lysosomal degradation of the epidermal growth factor receptor. Because of its bifunctional role, this protein may link heterotrimeric G protein signaling and vesicular trafficking.

Molekulargewicht:

Observed_MW: 112kDa

Calculated_MW: 110kDa/112kDa

Gen-ID: 23161

UniProt: Q9Y5W8

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling