Lipocalin 2 (LCN2) Antikörper

Details zu Produkt Nr. ABIN6567067
Target
Reaktivität
Human
116
56
53
9
6
2
1
Wirt
Kaninchen
104
59
10
8
2
1
Klonalität
Polyklonal
Konjugat
Unkonjugiert
33
15
5
5
4
4
4
4
4
2
2
2
2
1
1
1
1
1
1
1
Applikation
Immunofluorescence (IF), Western Blotting (WB)
107
94
60
26
16
13
10
10
9
8
7
5
3
2
2
2
2
1
1
1
1
1
1
1
Optionen
Immunogen Recombinant protein of human LCN2
Isotyp IgG
Reinigung Affinity purification
Target
Andere Bezeichnung LCN2 (LCN2 Antibody Abstract)
Hintergrund

Synonyms: 24p3,25 kDa alpha 2 microglobulin related subunit of MMP9,25 kDa alpha-2-microglobulin-related subunit of MMP-9,Alpha 2 microglobulin related protein,HGNC:6526,HNL,Lcn 2,Lcn2,Lipocalin-2,Migration stimulating factor inhibitor,MSFI,Neutrophil gelatinase associated lipocalin,Neutrophil gelatinase associated lipocalin precursor,Neutrophil gelatinase-associated lipocalin,NGAL,NGAL,Oncogene 24p3,Oncogenic lipocalin 24p3,p25,Siderocalin,siderocalin LCN2,SV40 induced 24P3 protein,Uterocalin

Background: This gene encodes a protein that belongs to the lipocalin family. Members of this family transport small hydrophobic molecules such as lipids, steroid hormones and retinoids. The protein encoded by this gene is a neutrophil gelatinase-associated lipocalin and plays a role in innate immunity by limiting bacterial growth as a result of sequestering iron-containing siderophores. The presence of this protein in blood and urine is an early biomarker of acute kidney injury. This protein is thought to be be involved in multiple cellular processes, including maintenance of skin homeostasis, and suppression of invasiveness and metastasis. Mice lacking this gene are more susceptible to bacterial infection than wild type mice.

Molekulargewicht

Observed_MW: 23kDa

Calculated_MW: 22kDa

Gen-ID 3934
UniProt P80188
Pathways Cellular Response to Molecule of Bacterial Origin, Transition Metal Ion Homeostasis
Applikations-hinweise WB 1:500 - 1:2000 IF 1:10 - 1:100
Beschränkungen Nur für Forschungszwecke einsetzbar
Konzentration 1 mg/mL
Buffer Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20°C. Avoid freeze / thaw cycles.
Bilder
Image no. 1 for anti-Lipocalin 2 (LCN2) antibody (ABIN6567067) Western blot analysis of extracts of A-549 cells, using LCN2 antibody.
Image no. 2 for anti-Lipocalin 2 (LCN2) antibody (ABIN6567067) Immunofluorescence analysis of A549 cells using LCN2 antibody.