IARS Antikörper (Isoleucyl-tRNA Synthetase)

Details for Product anti-IARS Antibody No. ABIN6566805
Target
Reaktivität
Human
18
4
4
3
3
2
2
2
2
2
1
Wirt
Kaninchen
10
8
Klonalität
Polyklonal
Applikation
Western Blotting (WB)
17
7
3
2
2
1
Optionen
Immunogen Recombinant protein of human IARS
Isotyp IgG
Reinigung Affinity purification
Target
Andere Bezeichnung IARS (IARS Antibody Abstract)
Hintergrund

Synonyms: FLJ20736,IARS,IARS1,IleRS,ILRS,IRS,Isoleucine tRNA ligase 1 cytoplasmic,Isoleucine tRNA ligase,Isoleucine tRNA synthetase ,Isoleucyl tRNA synthetase ,PRO0785

Background: Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAS, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Isoleucine-tRNA synthetase belongs to the class-I aminoacyl-tRNA synthetase family and has been identified as a target of autoantibodies in the autoimmune disease polymyositis/dermatomyositis. Alternatively spliced transcript variants have been found.

Molekulargewicht

Observed_MW: 160kDa

Calculated_MW: 144kDa

Gen-ID 3376
UniProt P41252
Applikations-hinweise WB 1:200 - 1:1000
Beschränkungen Nur für Forschungszwecke einsetzbar
Konzentration 1 mg/mL
Buffer Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20°C. Avoid freeze / thaw cycles.
Bilder
Image no. 1 for anti-Isoleucyl-tRNA Synthetase (IARS) antibody (ABIN6566805) Western blot analysis of extracts of various cell lines, using IARS antibody.