Synonyms: 1110005D17Rik,Coatomer epsilon subunit ,Coatomer protein complex subunit epsilon,Coatomer subunit epsilon,COPE,COPE,Cope1,Epsilon coat protein,Epsilon COP,Epsilon COP I,Epsilon subunit of coatomer protein complex ,Epsilon-coat protein,Epsilon-COP,FLJ13241
Background: The product of this gene is an epsilon subunit of coatomer protein complex. Coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles. It is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. Coatomer complex consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits. Alternatively spliced transcript variants encoding different isoforms have been identified.