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Glycerol Kinase Antikörper (AA 1-180)

Dieses Anti-Glycerol Kinase-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von Glycerol Kinase in ELISA, WB und IHC. Geeignet für Human, Maus und Ratte.
Produktnummer ABIN5692865

Kurzübersicht für Glycerol Kinase Antikörper (AA 1-180) (ABIN5692865)

Target

Alle Glycerol Kinase (GK) Antikörper anzeigen
Glycerol Kinase (GK)

Reaktivität

  • 59
  • 20
  • 18
  • 7
  • 6
  • 6
  • 4
  • 4
  • 4
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
Human, Maus, Ratte

Wirt

  • 72
  • 6
  • 4
Kaninchen

Klonalität

  • 80
  • 2
Polyklonal

Konjugat

  • 40
  • 10
  • 7
  • 5
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser Glycerol Kinase Antikörper ist unkonjugiert

Applikation

  • 53
  • 40
  • 14
  • 14
  • 13
  • 13
  • 10
  • 7
  • 6
  • 5
  • 4
  • 4
  • 4
  • 3
  • 2
  • 1
  • 1
ELISA, Western Blotting (WB), Immunohistochemistry (IHC)
  • Bindungsspezifität

    • 15
    • 7
    • 6
    • 6
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-180

    Verwendungszweck

    Anti-Glycerol kinase/GK Antibody Picoband®

    Marke

    Picoband™

    Kreuzreaktivität (Details)

    No cross-reactivity with other proteins.

    Produktmerkmale

    Rabbit IgG polyclonal antibody for Glycerol kinase detection. Tested with WB, IHC-P, Direct ELISA in Human,Mouse,Rat.

    Immunogen

    E. coli-derived human Glycerol kinase recombinant protein (Position: M1-S180).

    Isotyp

    IgG
  • Applikationshinweise

    Western blot, 0.1-0.5 μg/mL
    Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL
    ELISA, 0.1-0.5 μg/mL
    1. Dipple, K. M., Zhang, Y.-H., Huang, B.-L., McCabe, L. L., Dallongeville, J., Inokuchi, T., Kimura, M., Marx, H. J., Roederer, G. O., Shih, V., Yamaguchi, S., Yoshida, I., McCabe, E. R. B.Glycerol kinase deficiency: evidence for complexity in a single gene disorder. Hum. Genet. 109: 55-62, 2001. 2. Gaudet, D., Arsenault, S., Perusse, L., Vohl, M.-C., St.-Pierre, J., Bergeron, J., Despres, J.-P., Dewar, K., Daly, M. J., Hudson, T., Rioux, J. D. Glycerol as a correlate of impaired glucose tolerance: dissection of a complex system by use of a simple genetic trait. Am. J. Hum. Genet. 66: 1558-1568, 2000.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    Konzentration

    500 μg/mL

    Buffer

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • Target

    Glycerol Kinase (GK)

    Andere Bezeichnung

    GK

    Hintergrund

    Synonyms: Glycerol kinase, GK, Glycerokinase, ATP:glycerol 3-phosphotransferase, GK

    Tissue Specificity: Highly expressed in the liver, kidney and testis. Isoform 2 and isoform 3 are expressed specifically in testis and fetal liver, but not in the adult liver.

    Background: Glycerol kinase is a phosphotransferase enzyme involved in triglycerides and glycerophospholipids synthesis. The protein encoded by this gene belongs to the FGGY kinase family. This protein is a key enzyme in the regulation of glycerol uptake and metabolism. It catalyzes the phosphorylation of glycerol by ATP, yielding ADP and glycerol-3-phosphate. Mutations in this gene are associated with glycerol kinase deficiency (GKD). Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

    Molekulargewicht

    61 kDa

    Gen-ID

    2710

    UniProt

    P32189
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