ProSAPiP1 Antikörper (C-Term)
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- Target Alle ProSAPiP1 (PROSAPIP1) Produkte
- ProSAPiP1 (PROSAPIP1) (ProSAP-Interacting Protein 1 (PROSAPIP1))
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Bindungsspezifität
- C-Term
- Reaktivität
- Maus, Ratte, Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser ProSAPiP1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
- Spezifität
- This antibody detects Prosapip1. It will not cross-react with Prosapip2.
- Kreuzreaktivität (Details)
- Species reactivity (tested):Human, Mouse, Rat.
- Aufreinigung
- Peptide Affinity Chromatography
- Immunogen
- A 16 amino acid peptide from near the carboxy terminus of Human Prosapip1.
- Isotyp
- IgG
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- Applikationshinweise
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ELISA. Western blot: 1-2 μg/mL. Immunohistochemistry on Paraffin Sections. Recommended Positive Control. SK-N-SH Cell Lysate.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Buffer
- PBS containing 0.02 % Sodium Azide as preservative
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C
- Informationen zur Lagerung
- Store the antibody undiluted at 2-8 °C.
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- Target
- ProSAPiP1 (PROSAPIP1) (ProSAP-Interacting Protein 1 (PROSAPIP1))
- Andere Bezeichnung
- PROSAPIP1 (PROSAPIP1 Produkte)
- Hintergrund
- Prosapip1 is a binding partner of the postsynaptic density (PSD) protein ProSAP2/Shank3, a major scaffolding protein in excitatory brain synapses. Prosapip1 is thought to bind ProSAP2/Shank3 through ProSAP2/Shank3's PDZ domain and link it in turn to the Spine-associated Rap-Gap (SPAR). Prosapip1 shares significant homology with another PSD protein, PSD-Zip70, with both coding for a Fez1 domain that can be found in a total of four related protein, forming a novel family of scaffolding molecules termed 'Fezzins'. Recent studies show that Prosapip1 can be found in endocrine cells in which it is localized primarily in the hormone-storing compartment of these cells, suggesting that Prosapip1 may have other functions in non-neuronal cells.Synonyms: KIAA0552, ProSAP-interacting protein 1
- Gen-ID
- 9762
- NCBI Accession
- NP_055546
- UniProt
- O60299
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