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Glucose-6-Phosphate Dehydrogenase Antikörper (AA 315-515)

Der Kaninchen Polyklonal Anti-Glucose-6-Phosphate Dehydrogenase-Antikörper wurde für WB validiert. Er ist geeignet, Glucose-6-Phosphate Dehydrogenase in Proben von Human und Maus zu detektieren. Es ist 1 Publikation verfügbar.
Produktnummer ABIN3042413

Kurzübersicht für Glucose-6-Phosphate Dehydrogenase Antikörper (AA 315-515) (ABIN3042413)

Target

Alle Glucose-6-Phosphate Dehydrogenase (G6PD) Antikörper anzeigen
Glucose-6-Phosphate Dehydrogenase (G6PD)

Reaktivität

  • 91
  • 42
  • 24
  • 10
  • 7
  • 6
  • 4
  • 4
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
Human, Maus

Wirt

  • 121
  • 16
  • 13
Kaninchen

Klonalität

  • 125
  • 25
Polyklonal

Konjugat

  • 78
  • 24
  • 10
  • 6
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser Glucose-6-Phosphate Dehydrogenase Antikörper ist unkonjugiert

Applikation

  • 112
  • 59
  • 51
  • 32
  • 25
  • 23
  • 19
  • 15
  • 14
  • 14
  • 9
  • 8
  • 8
  • 7
  • 5
  • 4
  • 4
  • 1
Western Blotting (WB)
  • Bindungsspezifität

    • 16
    • 15
    • 8
    • 6
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 315-515

    Verwendungszweck

    Anti-Glucose 6 Phosphate Dehydrogenase/G6PD Antibody Picoband®

    Kreuzreaktivität (Details)

    No cross-reactivity with other proteins

    Produktmerkmale

    Anti-Glucose 6 Phosphate Dehydrogenase/G6PD Antibody Picoband® (ABIN3042413). Tested in WB applications. This antibody reacts with Human;Mouse. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    Aufreinigung

    Immunogen affinity purified.

    Immunogen

    E.coli-derived human G6PD recombinant protein (Position: E315-L515). Human G6PD shares 95% and 96% amino acid (aa) sequences identity with mouse and rat G6PD, respectively.

    Isotyp

    IgG
  • Applikationshinweise

    Western blot, 0.1-0.5 μg/mL, Human, Mouse
    1. Aster J, Kumar V, Robbins SL, Abbas AK, Fausto N, Cotran RS (2010). Robbins and Cotran pathologic basis of disease. Saunders/Elsevier. pp. Kindle Locations 33340-33341. 2. Takizawa, T., Huang, I.-Y., Ikuta, T., Yoshida, A. Human glucose-6-phosphate dehydrogenase: primary structure and cDNA cloning. Proc. Nat. Acad. Sci. 83: 4157-4161, 1986.

    Kommentare

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    Konzentration

    500 μg/mL

    Buffer

    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.01 mg Sodium azide.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handhabung

    Avoid repeated freezing and thawing.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • Hu, Zhang, Tang, Su, Li, Chen, Zhang, Cai, Zhu: "Variant G6PD levels promote tumor cell proliferation or apoptosis via the STAT3/5 pathway in the human melanoma xenograft mouse model." in: BMC cancer, Vol. 13, Issue 1, pp. 251, (2014) (PubMed).

  • Target

    Glucose-6-Phosphate Dehydrogenase (G6PD)

    Andere Bezeichnung

    G6PD

    Hintergrund

    Synonyms: Glucose-6-phosphate 1-dehydrogenase,G6PD,1.1.1.49,G6PD,

    Tissue Specificity: Isoform Long is found in lymphoblasts, granulocytes and sperm.

    Background: Glucose-6-phosphate dehydrogenase, also known as G6PD or G6PDH, is an enzyme that in humans is encoded by the G6PD gene. It is mapped to Xq28. G6PD plays a key role in the production of ribose 5-phosphate and the generation of NADPH in the hexose monophosphate pathway. Because this pathway is the only NADPH-generation process in mature red cells, which lack the citric adid cycle, a genetic deficiency of G6PD is often associated with adverse physiologic effects. It has been found that aldosterone decreased G6PD expression and activity, resulting in increased oxidant stress and decreased nitric oxide levels, similar to what is observed in G6PD-deficient endothelial cells.

    Sequence Similarities: Belongs to the glucose-6-phosphate dehydrogenase family.

    Molekulargewicht

    59 kDa

    Gen-ID

    2539

    UniProt

    P11413

    Pathways

    Regulation of Systemic Arterial Blood Pressure by Hormones
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