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Glucose-6-Phosphate Dehydrogenase Antikörper (AA 315-515)

G6PD Reaktivität: Human, Maus WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN3042413
  • Target Alle Glucose-6-Phosphate Dehydrogenase (G6PD) Antikörper anzeigen
    Glucose-6-Phosphate Dehydrogenase (G6PD)
    Bindungsspezifität
    • 16
    • 15
    • 8
    • 6
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 315-515
    Reaktivität
    • 91
    • 42
    • 24
    • 10
    • 7
    • 6
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Human, Maus
    Wirt
    • 121
    • 16
    • 13
    Kaninchen
    Klonalität
    • 125
    • 25
    Polyklonal
    Konjugat
    • 78
    • 24
    • 10
    • 6
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Glucose-6-Phosphate Dehydrogenase Antikörper ist unkonjugiert
    Applikation
    • 112
    • 59
    • 51
    • 32
    • 25
    • 23
    • 19
    • 15
    • 14
    • 14
    • 9
    • 8
    • 8
    • 7
    • 5
    • 4
    • 4
    • 1
    Western Blotting (WB)
    Verwendungszweck
    Anti-Glucose 6 Phosphate Dehydrogenase/G6PD Antibody Picoband®
    Kreuzreaktivität (Details)
    No cross-reactivity with other proteins
    Produktmerkmale
    Anti-Glucose 6 Phosphate Dehydrogenase/G6PD Antibody Picoband® (ABIN3042413). Tested in WB applications. This antibody reacts with Human;Mouse. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
    Aufreinigung
    Immunogen affinity purified.
    Immunogen
    E.coli-derived human G6PD recombinant protein (Position: E315-L515). Human G6PD shares 95% and 96% amino acid (aa) sequences identity with mouse and rat G6PD, respectively.
    Isotyp
    IgG
    Top Product
    Discover our top product G6PD Primärantikörper
  • Applikationshinweise
    Western blot, 0.1-0.5 μg/mL, Human, Mouse
    1. Aster J, Kumar V, Robbins SL, Abbas AK, Fausto N, Cotran RS (2010). Robbins and Cotran pathologic basis of disease. Saunders/Elsevier. pp. Kindle Locations 33340-33341. 2. Takizawa, T., Huang, I.-Y., Ikuta, T., Yoshida, A. Human glucose-6-phosphate dehydrogenase: primary structure and cDNA cloning. Proc. Nat. Acad. Sci. 83: 4157-4161, 1986.
    Kommentare

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    Konzentration
    500 μg/mL
    Buffer
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.01 mg Sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • Hu, Zhang, Tang, Su, Li, Chen, Zhang, Cai, Zhu: "Variant G6PD levels promote tumor cell proliferation or apoptosis via the STAT3/5 pathway in the human melanoma xenograft mouse model." in: BMC cancer, Vol. 13, Issue 1, pp. 251, (2014) (PubMed).

  • Target
    Glucose-6-Phosphate Dehydrogenase (G6PD)
    Andere Bezeichnung
    G6PD (G6PD Produkte)
    Hintergrund

    Synonyms: Glucose-6-phosphate 1-dehydrogenase,G6PD,1.1.1.49,G6PD,

    Tissue Specificity: Isoform Long is found in lymphoblasts, granulocytes and sperm.

    Background: Glucose-6-phosphate dehydrogenase, also known as G6PD or G6PDH, is an enzyme that in humans is encoded by the G6PD gene. It is mapped to Xq28. G6PD plays a key role in the production of ribose 5-phosphate and the generation of NADPH in the hexose monophosphate pathway. Because this pathway is the only NADPH-generation process in mature red cells, which lack the citric adid cycle, a genetic deficiency of G6PD is often associated with adverse physiologic effects. It has been found that aldosterone decreased G6PD expression and activity, resulting in increased oxidant stress and decreased nitric oxide levels, similar to what is observed in G6PD-deficient endothelial cells.

    Sequence Similarities: Belongs to the glucose-6-phosphate dehydrogenase family.

    Molekulargewicht
    59 kDa
    Gen-ID
    2539
    UniProt
    P11413
    Pathways
    Regulation of Systemic Arterial Blood Pressure by Hormones
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