ADRA2A Antikörper (Middle Region)

Produktnummer ABIN3029881

Produktdetails anti-ADRA2A Antikörper

Target: ADRA2A (Alpha-2A Adrenergic Receptor (ADRA2A))

Bindungsspezifität: Middle Region

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ADRA2A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: Antigen affinity

Immunogen: An amino acid sequence from the middle region of human alpha 2a Adrenergic Receptor (ILVYVRIYQIAKRRTR) was used as the immunogen for this alpha 2a Adrenergic Receptor antibody (100% homologous in human, mouse and rat).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: The stated application concentrations are suggested starting amounts. Titration of the Alpha 2a Adrenergic Receptor antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: -20 °C

Informationen zur Lagerung: After reconstitution, the Alpha 2a Adrenergic Receptor antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Details zu ADRA2A

Target: ADRA2A (Alpha-2A Adrenergic Receptor (ADRA2A))

Andere Bezeichnung: alpha 2a Adrenergic Receptor (ADRA2A Produkte)

Synonyme: ADRA2A antikoerper, AW122659 antikoerper, Adra-2 antikoerper, Adra-2a antikoerper, alpha(2A)AR antikoerper, alpha2-C10 antikoerper, alpha2A antikoerper, alpha2A-AR antikoerper, ADRA2 antikoerper, ADRA2R antikoerper, ADRAR antikoerper, ALPHA2AAR antikoerper, ZNF32 antikoerper, CA2-47 antikoerper, RATRG20 antikoerper, RG20 antikoerper, PORA2AR antikoerper, adrenoceptor alpha 2A antikoerper, alpha-2A adrenergic receptor-like antikoerper, adrenergic receptor, alpha 2a antikoerper, adra2a antikoerper, ADRA2A antikoerper, LOC100414445 antikoerper, Adra2a antikoerper

Hintergrund: The alpha 2A adrenergic receptor is a member of the G protein-coupled receptor superfamily which include three highly homologous subtypes: alpha2A, alpha2B, and alpha2C. These receptors have a critical role in regulating neurotransmitter release from sympathetic nerves and from adrenergic neurons in the central nervous system. Studies in mouse revealed that both the alpha2A and alpha2C subtypes were required for normal presynaptic control of transmitter release from sympathetic nerves in the heart and from central noradrenergic neurons, the alpha2A subtype inhibited transmitter release at high stimulation frequencies, whereas the alpha2C subtype modulated neurotransmission at lower levels of nerve activity. This gene encodes alpha2A subtype and it contains no introns in either its coding or untranslated sequences. Alpha2 adrenergic receptors mediate the catecholamine-induced inhibition of adenylate cyclase through the action of G proteins.

UniProt: P08913

Pathways: EGFR Signaling Pathway, Negative Regulation of Hormone Secretion, Carbohydrate Homeostasis, cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling, Negative Regulation of Transporter Activity