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CAD Antikörper (C-Term)

CAD Reaktivität: Human WB, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2855032
  • Target Alle CAD Antikörper anzeigen
    CAD (Carbamoyl-Phosphate Synthetase 2, Aspartate Transcarbamylase, and Dihydroorotase (CAD))
    Bindungsspezifität
    • 10
    • 8
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reaktivität
    • 51
    • 21
    • 9
    • 7
    • 5
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Wirt
    • 51
    • 5
    Kaninchen
    Klonalität
    • 48
    • 8
    Polyklonal
    Konjugat
    • 44
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CAD Antikörper ist unkonjugiert
    Applikation
    • 33
    • 24
    • 20
    • 18
    • 16
    • 13
    • 5
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Kreuzreaktivität
    Human, Maus
    Produktmerkmale
    Rabbit Polyclonal antibody to CAD (carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase)
    CAD antibody [C2C3], C-term
    Aufreinigung
    Purified by antigen-affinity chromatography.
    Immunogen
    Recombinant protein encompassing a sequence within the C-terminus region of human CAD. The exact sequence is proprietary.
    Isotyp
    IgG
    Top Product
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  • Applikationshinweise
    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    Kommentare

    Positive Control: 293T , C2C12

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    0.41 mg/mL
    Buffer
    1XPBS ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
    Konservierungsmittel
    Thimerosal (Merthiolate)
    Vorsichtsmaßnahmen
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Target
    CAD (Carbamoyl-Phosphate Synthetase 2, Aspartate Transcarbamylase, and Dihydroorotase (CAD))
    Andere Bezeichnung
    carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase (CAD Produkte)
    Hintergrund
    The de novo synthesis of pyrimidine nucleotides is required for mammalian cells to proliferate. This gene encodes a trifunctional protein which is associated with the enzymatic activities of the first 3 enzymes in the 6-step pathway of pyrimidine biosynthesis: carbamoylphosphate synthetase (CPS II), aspartate transcarbamoylase, and dihydroorotase. This protein is regulated by the mitogen-activated protein kinase (MAPK) cascade, which indicates a direct link between activation of the MAPK cascade and de novo biosynthesis of pyrimidine nucleotides.

    Cellular Localization: Cytoplasm
    Molekulargewicht
    243 kDa
    Gen-ID
    790
    UniProt
    P27708
    Pathways
    Production of Molecular Mediator of Immune Response, Ribonucleoside Biosynthetic Process
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