DAZ4 Antikörper (Center)

Produktnummer ABIN2797811

Produktdetails anti-DAZ4 Antikörper

Target: DAZ4 (Deleted In Azoospermia 4 (DAZ4))

Bindungsspezifität: AA 90-119, Center

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DAZ4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Verwendungszweck: Rabbit Anti-Human DAZ4 (Center) Antibody

Immunogen: This DAZ4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 90-119 amino acids from the Central region of human DAZ4.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Western Blot, Immunohistochemistry
Recommended Dilutions
WB: 1:1000, IHC: 1:10-50DAZ4 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: 2-8°C (short-term), -20°C (long-term)

Details zu DAZ4

Target: DAZ4 (Deleted In Azoospermia 4 (DAZ4))

Andere Bezeichnung: DAZ4 (DAZ4 Produkte)

Synonyme: pDP1680 antikoerper, pDP1681 antikoerper, DAZ4 antikoerper, deleted in azoospermia 4 antikoerper, DAZ4 antikoerper

Hintergrund:

Target Description: This gene is a member of the DAZ gene family and is a candidate for the human Y-chromosomal azoospermia factor (AZF). Its expression is restricted to premeiotic germ cells, particularly in spermatogonia. It encodes an RNA-binding protein that is important for spermatogenesis. Four copies of this gene are found on chromosome Y within palindromic duplications, one pair of genes is part of the P2 palindrome and the second pair is part of the P1 palindrome. Each gene contains a 2.4 kb repeat including a 72-bp exon, called the DAZ repeat, the number of DAZ repeats is variable and there are several variations in the sequence of the DAZ repeat. Each copy of the gene also contains a 10.8 kb region that may be amplified, this region includes five exons that encode an RNA recognition motif (RRM) domain. This gene contains two copies of the 10.8 kb repeat. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq].

Gene Symbol: DAZ4

Molekulargewicht: 64785 Da

Gen-ID: 57135

UniProt: Q86SG3