LGALS3BP Antikörper (Middle Region)

Produktnummer ABIN2785877

Produktdetails anti-LGALS3BP Antikörper

Target: LGALS3BP (Lectin, Galactoside-Binding, Soluble, 3 Binding Protein (LGALS3BP))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LGALS3BP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: NLSLYWSHEA LFQKKTLQAL EFHTVPFQLL ARYKGLNLTE DTYKPRIYTS

Homologie: Cow: 83%, Dog: 83%, Human: 100%, Mouse: 100%, Rat: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against LGALS3BP. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human LGALS3BP

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 585 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu LGALS3BP

Target: LGALS3BP (Lectin, Galactoside-Binding, Soluble, 3 Binding Protein (LGALS3BP))

Andere Bezeichnung: LGALS3BP (LGALS3BP Produkte)

Hintergrund: The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. LGALS3BP has been found elevated in the serum of patients with cancer and in those infected by the human immunodeficiency virus (HIV). It appears to be implicated in immune response associated with natural killer (NK) and lymphokine-activated killer (LAK) cell cytotoxicity. The native protein binds specifically to a human macrophage-associated lectin known as Mac-2 and also binds galectin 1.The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. LGALS3BP has been found elevated in the serum of patients with cancer and in those infected by the human immunodeficiency virus (HIV). It appears to be implicated in immune response associated with natural killer (NK) and lymphokine-activated killer (LAK) cell cytotoxicity. Using fluorescence in situ hybridization the full length 90K cDNA has been localized to chromosome 17q25. The native protein binds specifically to a human macrophage-associated lectin known as Mac-2 and also binds galectin 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: 90K, MAC-2-BP, BTBD17B
Protein Interaction Partner: GIGYF2, PRRC2C, CCT5, TUBB, CRTC2, RAVER1, TUBA1C, ENAH, CEP55, XRN2, CEP250, MAGED2, CCT8, CCT2, CCT4, CCT7, TUBGCP3, TUBB4B, TRAP1, BAG2, RPL23, IRS4, TUBA1A, MOGS, CCT3, TCP1, RPS4X, RPL38, HSPD1, HSP90AB1, HSP90AA1, HSPA8, HSPA5, HSPA1A, HNRNPU, CCT6A
Protein Size: 585

Molekulargewicht: 63 kDa

Gen-ID: 3959

NCBI Accession: NM_005567, NP_005558

UniProt: Q08380