Integrin beta 7 Antikörper (PE)
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- Target Alle Integrin beta 7 (ITGB7) Antikörper anzeigen
- Integrin beta 7 (ITGB7)
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Reaktivität
- Human, Maus
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Wirt
- Ratte
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Klonalität
- Monoklonal
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Konjugat
- Dieser Integrin beta 7 Antikörper ist konjugiert mit PE
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Applikation
- Flow Cytometry (FACS)
- Kreuzreaktivität
- Schimpanse, Pavian, Cynomolgus, Rhesusaffen
- Aufreinigung
- The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.
- Klon
- FIB504
- Isotyp
- IgG2a kappa
- Top Product
- Discover our top product ITGB7 Primärantikörper
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Buffer
- Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Protect from prolonged exposure to light. Do not freeze.
- Lagerung
- 4 °C
- Informationen zur Lagerung
- The antibody solution should be stored undiluted between 2°C and 8°C.
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- Target
- Integrin beta 7 (ITGB7)
- Andere Bezeichnung
- Integrin Beta7 (ITGB7 Produkte)
- Hintergrund
- Integrin β7 is a 130 kD glycoprotein also known as integin βp. It is a member of the Ig superfamily. In association with integrin α4 or αE chain, β7 forms α4/β7 or αE/β7 heterodimer. α4/β7 (CD49d/β7, LPAM-1) is expressed on the majority of peripheral lymphocytes, on small subsets of thymocytes, and bone marrow progenitors. LPAM-1 binds to several ligands, VCAM-1, MAdCAM-1 and fibronectin, and is involved in lymphocyte adhesion and some hematopoietic progenitor cells migration. αE/β7 (CD103/β7,αIEL/β7) is expressed on intestinal intraepithelial lymphocytes (IEL), dendritic epidermal T cells, T regulatory cells, a subset of CD8+ T cells in lymph nodes and lamina propria. CD103/β7 complex is thought to play a role in lymphocyte retention via interaction with its ligand E-Cadherin.
- Pathways
- Integrin Complex
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