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CD28 Antikörper (PE)

CD28 Reaktivität: Human FACS Wirt: Maus Monoclonal CD28-2 PE

Produktnummer ABIN2663307

Datenblatt (PDF)

Target Alle CD28 Antikörper anzeigen

CD28
Reaktivität
181

118

53

37

22

16

12

12

7

7

7

6

2

1

1

1

1

1
Human
Wirt
154

76

33

12

10

3

2
Maus
Passende Sekundärantikörper
Klonalität
215

68

4
Monoklonal
Konjugat
110

32

28

20

15

6

5

5

4

4

3

3

3

3

3

3

3

2

2

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1
Dieser CD28 Antikörper ist konjugiert mit PE
Applikation
217

89

60

50

41

35

35

26

23

17

13

7

7

6

6

6

5

4

4

4

4

4

3

2

2

2

2

1

1

1

1

1

1

1

1
Flow Cytometry (FACS)

Kreuzreaktivität

Schimpanse, Pavian, Cynomolgus, Rhesusaffen, Pigtailed Macaque, Capuchin Monkey, Sooty mangabey (Cercocebus atys), Squirrel Monkey (Saimiri spec.)

Aufreinigung

The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.

Klon

CD28-2

Isotyp

IgG1 kappa

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anti-CD28 (CD28) (AA 1-120) antibody
CD28 Reaktivität: Human, Maus, Ratte FACS, WB, ELISA, IHC (fro), IF (p), IHC (p), IF (cc) Wirt: Kaninchen Polyclonal unconjugated

anti-CD28 (CD28) antibody
CD28 Reaktivität: Human, Non-Human Primate FACS, WB, IP, IHC (fro), ICC Wirt: Maus Monoclonal CD28-2 unconjugated

anti-CD28 (CD28) antibody (FITC)
CD28 Reaktivität: Human, Non-Human Primate FACS Wirt: Maus Monoclonal CD28-2 FITC

anti-CD28 (CD28) antibody
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anti-CD28 (CD28) (AA 19-152) antibody
CD28 Reaktivität: Human FACS, ELISA Wirt: Kaninchen Monoclonal DM61 unconjugated Recombinant Antibody

anti-CD28 (CD28) antibody
CD28 Reaktivität: Ratte FACS, IP Wirt: Maus Monoclonal JJ319 unconjugated

anti-CD28 (CD28) antibody (PE)
CD28 Reaktivität: Ratte FACS Wirt: Maus Monoclonal JJ319 PE

anti-CD28 (CD28) antibody (PerCP)
CD28 Reaktivität: Human, Non-Human Primate FACS Wirt: Maus Monoclonal CD28-2 PerCP

anti-CD28 (CD28) antibody (APC)
CD28 Reaktivität: Human, Non-Human Primate FACS Wirt: Maus Monoclonal CD28-2 APC

anti-CD28 (CD28) antibody (PE)
CD28 Reaktivität: Human, Non-Human Primate FACS Wirt: Maus Monoclonal CD28-2 PE

Applikationshinweise

Optimal working dilution should be determined by the investigator.

Beschränkungen

Nur für Forschungszwecke einsetzbar
Konzentration

0.2 mg/mL

Buffer

Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung

Protect from prolonged exposure to light. Do not freeze.

Lagerung

4 °C

Informationen zur Lagerung

The antibody solution should be stored undiluted between 2°C and 8°C.
Target

CD28

Andere Bezeichnung

CD28 (CD28 Produkte)

Hintergrund

CD28 is a 44 kD disulfide-linked homodimeric type I glycoprotein. It is a member of the immunoglobulin superfamily and is also known as T44 or Tp44. CD28 is expressed on most T lineage cells, NK cell subsets, and plasma cells. CD28 binds both CD80 and CD86 using a highly conserved motif MYPPY in the CDR3-like loop. CD28 is considered a major co-stimulatory molecule, inducing T lymphocyte activation and IL-2 synthesis, and preventing cell death. In vitro studies indicate that ligation of CD28 on T cells by CD80 and CD86 on antigen presenting cells provides a costimulatory signal required for T cell activation and proliferation.

Pathways

T-Zell Rezeptor Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response