CMV ICP36 Antikörper

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Cytomegalovirus (CMV)
Klonalität (Klon)
Monoklonal ()
Immunofluorescence (IF), Western Blotting (WB)
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Hersteller Produkt- Nr.
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Klon CH16
Isotyp IgG2b kappa
Reinigung Protein G agarose affinity chromatography
Hintergrund Mouse monoclonal antibody to ICP36 of Cytomegalovirus. This antibody originates from ascites fluids and is purified by protein G agarose affinity chromatography.
Applikations-hinweise Reactive with ICP36 of Cytomegalovirus in immunofluorescence (IFA) and western blot assays at 10 ug/ml. 
Beschränkungen Nur für Forschungszwecke einsetzbar
Konzentration 1.0 mg/ml
Buffer Phosphate Buffered Saline pH 7.4 (no azide)
Konservierungs-mittel Azide free
Lagerung -20 °C
Produkt verwendet in: Fiorentini, Luganini, DellOste, Lorusso, Cervi, Caccuri, Bonardelli, Landolfo, Caruso, Gribaudo et al.: "Human cytomegalovirus productively infects lymphatic endothelial cells and induces a secretome that promotes angiogenesis and lymphangiogenesis through interleukin-6 and granulocyte-macrophage ..." in: The Journal of general virology, Vol. 92, Issue Pt 3, pp. 650-60, 2011 (PubMed).

Tran, Kamil, Coen, Spector et al.: "Inactivation and disassembly of the anaphase-promoting complex during human cytomegalovirus infection is associated with degradation of the APC5 and APC4 subunits and does not require UL97-mediated ..." in: Journal of virology, Vol. 84, Issue 20, pp. 10832-43, 2010 (PubMed).

Kapasi, Clark, Tran, Spector: "Recruitment of cdk9 to the immediate-early viral transcriptosomes during human cytomegalovirus infection requires efficient binding to cyclin T1, a threshold level of IE2 86, and active transcription." in: Journal of virology, Vol. 83, Issue 11, pp. 5904-17, 2009 (PubMed).

Sanders, Clark, Morello, Spector: "Development of cell lines that provide tightly controlled temporal translation of the human cytomegalovirus IE2 proteins for complementation and functional analyses of growth-impaired and nonviable IE2 mutant viruses." in: Journal of virology, Vol. 82, Issue 14, pp. 7059-77, 2008 (PubMed).

Sanders, Del Rosario, White, Spector: "Internal deletions of IE2 86 and loss of the late IE2 60 and IE2 40 proteins encoded by human cytomegalovirus affect the levels of UL84 protein but not the amount of UL84 mRNA or the loading and distribution of the mRNA on polysomes." in: Journal of virology, Vol. 82, Issue 22, pp. 11383-97, 2008 (PubMed).

White, Del Rosario, Sanders, Spector: "The IE2 60-kilodalton and 40-kilodalton proteins are dispensable for human cytomegalovirus replication but are required for efficient delayed early and late gene expression and production of infectious virus." in: Journal of virology, Vol. 81, Issue 6, pp. 2573-83, 2007 (PubMed).

Allgemeine Veröffentlichungen Mocarski, Pereira, Michael: "Precise localization of genes on large animal virus genomes: use of lambda gt11 and monoclonal antibodies to map the gene for a cytomegalovirus protein family." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 82, Issue 4, pp. 1266-70, 1985 (PubMed).

Pereira, Hoffman, Gallo, Cremer: "Monoclonal antibodies to human cytomegalovirus: three surface membrane proteins with unique immunological and electrophoretic properties specify cross-reactive determinants." in: Infection and immunity, Vol. 36, Issue 3, pp. 924-32, 1982 (PubMed).

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