Deleted In Azoospermia 4 (DAZ4) Antikörper (Cy5)

Details zu Produkt Nr. ABIN1705117
Antigen
  • pDP1680
  • pDP1681
  • DAZ4
  • deleted in azoospermia 4
  • DAZ4
Reaktivität
Human, Maus, Ratte (Rattus)
56
20
20
4
3
3
2
2
2
2
Wirt
Kaninchen
55
1
Klonalität
Polyklonal
Konjugat
Cy5
4
3
3
2
2
2
2
2
2
2
2
1
1
1
1
1
1
Applikation
Immunofluorescence (Paraffin-embedded Sections) (IF (p))
36
26
19
12
8
1
Optionen
Immunogen KLH conjugated synthetic peptide derived from human DAZ4
Isotyp IgG
Reinigung Purified by Protein A.
Antigen
Andere Bezeichnung Daz4 (DAZ4 Antibody Abstract)
Hintergrund

Spermatogenesis is the process by which male spermatogonia develop into mature spermatozoa. DAZ (deleted in azoospermia) are RNA-binding proteins that play an essential role in spermatogenesis. DAZ proteins influence the first stages of spermatogenesis and the maintenance of germ cell populations. DAZ proteins (DAZ1, DAZ2, DAZ3, DAZ4 and DAZ5) are encoded by separate genes on chromosome Y, each of which contain an AZFc domain in their coding region. DAZ proteins localize to the nucleus of spermatogonia, but relocate to the cytoplasm during meiosis. DAZ proteins contain an RRM (RNA recognition motif) domain that may regulate mRNA translation by binding to the 3’UTR. Deletions in the genes encoding DAZ proteins may cause azoospermia or oligospermia which can lead to male infertility. DAZ4 (deleted in azoospermia 4), also known as pDP1680 or pDP1681, is a 579 amino acid testis specific protein that contains nine DAZ-like domains and two RNA recognition motifs (RRM). DAZ4 exists as two alternatively spliced isoforms.

Synonyms: DAZ4, Deleted in azoospermia 4, Deleted in azoospermia protein 4.

Applikations-hinweise IF(IHC-P) 1:50-200
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Lagerung 4 °C
Informationen zur Lagerung Store at 4°C
Haltbarkeit 12 months
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