FLNC Antikörper (Filamin C, gamma) (pSer2233) (Cy5)

Details for Product anti-FLNC Antibody No. ABIN1705032
Antigen
  • 1110055E19Rik
  • ABP-280
  • ABPL
  • Fln2
  • ABP280A
  • ABPA
  • FLN2
  • MFM5
  • MPD4
  • filamin C
  • filamin C L homeolog
  • filamin C, gamma
  • FLNC
  • flnc.L
  • flnc
  • Flnc
Epitop
pSer2233
15
11
3
3
1
1
1
Reaktivität
Human, Maus, Ratte (Rattus)
48
38
35
2
2
2
2
2
1
1
1
1
1
Wirt
Kaninchen
46
2
Klonalität
Polyklonal
Konjugat
Dieser FLNC Antikörper ist konjugiert mit Cy5
3
3
3
3
2
2
2
2
2
2
2
2
2
1
Applikation
Immunofluorescence (Paraffin-embedded Sections) (IF (p))
22
15
6
5
3
3
2
1
Optionen
Immunogen KLH conjugated synthetic phosphopeptide derived from human FLNC around the phosphorylation site of Ser2233
Isotyp IgG
Reinigung Purified by Protein A.
Plasmids, Primers & others Plasmide, Primers & weitere FLNC products on genomics-online (e.g. as negative or positive controls)
Antigen
Andere Bezeichnung Flnc (FLNC Antibody Abstract)
Hintergrund

Filamins are Actin-binding proteins which contain an N-terminal Actin-binding domain, a membrane glycoprotein domain and a C-terminal self-association domain. Filamins help reshape the cytoskeleton by forming flexible cross-links between two Actin filaments, which maintain membrane integrity during force application. Filamins also participate in signal transduction pathways associated with cell motility, adhesion, differentiation and survival, and force transduction. The filamin family is comprised of Filamin 1, Filamin 2 and Filamin 3. Filamin 2, also designated Filamin C, is a skeletal- and cardiac-muscle specific form of Filamin, which binds ©-sarcoglycan and ∂,-sarcoglycan, but not å-sarcoglycan or â^-sarcoglycan. Muscular dystrophy, an inherited group of disorders resulting in progressive weakness of muscles in the body, is associated with irregular subcellular localization of Filamin 2 caused by a deficiency in KY, a protein that interacts with Filamin 2.

Synonyms: FLNC phospho S2233, p-Filamin 2 phospho S2233, p-FLNC phospho S2233, ABP 280, ABP L, ABPL, Actin binding like protein, Actin binding protein 280, Filamin 2, Filamin2, Filamin-2, Filamin C, Filamin C gamma, FLJ10186, FLN 2, FLN2, FLNC, Gamma actin binding protein, Gamma filamin, Protein FLNc, FLNC_HUMAN, Filamin-C, FLN-C, ABP-280-like protein, ABP-L, Actin-binding-like protein.

Gen-ID 2318
Applikations-hinweise IF(IHC-P) 1:50-200
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Lagerung 4 °C
Informationen zur Lagerung Store at 4°C
Haltbarkeit 12 months
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