ARP1 Actin-Related Protein 1, Centractin (Yeast) (ACTR1) Antikörper (Cy5)

Details zu Produkt Nr. ABIN1704990
Antigen
  • Actr1b
  • hm:zehn1110
  • wu:fc22g09
  • wu:fc56d01
  • wu:fy52e08
  • zehn1110
  • zgc:56317
  • ARP1 actin related protein 1, centractin
  • actr1
Reaktivität
Human, Maus, Ratte (Rattus)
14
14
14
Wirt
Kaninchen
14
Klonalität
Polyklonal
Konjugat
Cy5
1
1
1
1
1
1
1
1
1
1
1
1
1
Applikation
Immunofluorescence (Paraffin-embedded Sections) (IF (p))
12
3
3
Optionen
Immunogen KLH conjugated synthetic peptide derived from human SKR1/ACTR1
Isotyp IgG
Reinigung Purified by Protein A.
Antigen
Andere Bezeichnung Actr1
Hintergrund

Members of the transforming growth factor b superfamily bind to a pair of transmembrane proteins, known as receptor types I and II, which contain serine/threonine kinases and associate to form a signaling complex (1). Activin has been shown to bind a heteromeric noncovalent complex, which consists of a type I receptor, ACTR-IA (also designated ACVRI and ALK-2) or ACTR-IB (also designated ALK-4 and SKR2), and a type II receptor, ACTR-IIA (also designated ACVR2A) or ACTR-IIB (also designated ACVR2B) (1â€"6). Both receptor types are highly expressed in brain (5). The activin receptor family members are thought to mediate distinct effects on gene expression, cell differentiation, and morpho- genesis in a dose dependent fashion (5,6).

Subcellular location: Extracellular

Synonyms: Activin Receptor Type IA, Activin A receptor type I, Activin A receptor type II like kinase 2, Activin receptor type I, Activin receptor type-1, Activin receptor-like kinase 2, ACTR1, ACTR 1, ACTR-1, ACTR-I, ACTRI, ACVR 1, ACVR1, ACVR1_HUMAN, ACVR1A, ACVRLK 2, ACVRLK2, ALK 2, ALK-2, ALK2, FOP, Hydroxyalkyl protein kinase, Serine/threonine protein kinase receptor R1, Serine/threonine-protein kinase receptor R1, SKR 1, SKR1, TGF-B superfamily receptor type I, TGFB superfamily receptor type I, TSR-I, TSRI, TSRI.

Gen-ID 90
Applikations-hinweise IF(IHC-P) 1:50-200
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Lagerung 4 °C
Informationen zur Lagerung Store at 4°C
Haltbarkeit 12 months
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