Galactosamine (N-Acetyl)-6-Sulfate Sulfatase (GALNS) Antikörper (Cy5)

Details zu Produkt Nr. ABIN1704911
Antigen
  • GALNAC6S
  • GAS
  • GalN6S
  • MPS4A
  • mFLJ00319
  • galns
  • zgc:158385
  • galactosamine (N-acetyl)-6-sulfatase
  • galactosamine (N-acetyl)-6-sulfate sulfatase
  • N-acetylgalactosamine-6-sulfatase
  • galactosamine (N-acetyl)-6-sulfatase L homeolog
  • GALNS
  • Galns
  • Celly_0425
  • galns.L
  • galns
Reaktivität
Human, Maus, Ratte (Rattus)
103
41
36
Wirt
Kaninchen
89
17
3
Klonalität
Polyklonal
Konjugat
Cy5
8
7
7
3
3
3
2
2
2
2
2
1
1
1
1
1
1
Applikation
Immunofluorescence (Paraffin-embedded Sections) (IF (p))
78
45
37
19
17
16
12
11
5
4
1
1
Optionen
Immunogen KLH conjugated synthetic peptide derived from human GALNS
Isotyp IgG
Reinigung Purified by Protein A.
Antigen
Andere Bezeichnung Galns (GALNS Antibody Abstract)
Hintergrund

Chondroitinase is a 522 amino acid protein that localizes to the lysosome and functions as an exohydrolase that is essential for the degradation of glycosaminoglycans, keratan sulfate and chondroitin 6-sulfate. Using calcium as a cofactor, Chondroitinase, which exists as a disulfide linked oligomer, catalyzes the hydrolysis of the 6-sulfate group on target substrates. Defects in the gene encoding Chondroitinase are the cause of mucopolysaccharidosis type 4A (MPS4A), an autosomal recessive lysosomal storage disease that is characterized by the intracellular accumulation of keratan sulfate and chondroitin-6-sulfate and is associated with dental anomalies, short stature and, in some cases, death in the second or third decade of life.

Synonyms: Chondroitinase, Chondroitinsulfatase, FLJ00319, FLJ17434, FLJ42844, FLJ98217, Galactosamine N acetyl 6 sulfate sulfatase, Galactose 6 sulfate sulfatase, GALNAC6S, GalNAc6S sulfatase, GAS, mFLJ00319, MPS4A, N acetylgalactosamine 6 sulfatase, N acetylgalactosamine 6 sulfate sulfatase, GALNS_HUMAN.

Gen-ID 2588
Pathways Glycosaminoglycan Metabolic Process
Applikations-hinweise IF(IHC-P) 1:50-200
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Lagerung 4 °C
Informationen zur Lagerung Store at 4°C
Haltbarkeit 12 months
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