GPR124 Antikörper (G Protein-Coupled Receptor 124) (Cy5)

Details for Product anti-GPR124 Antibody No. ABIN1704906
Antigen
  • TEM5
  • 8430414O08Rik
  • 9530074E10Rik
  • Tem5
  • mKIAA1531
  • MGC69043
  • si:dkey-208c22.2
  • GPR124
  • adhesion G protein-coupled receptor A2
  • adhesion G protein-coupled receptor A2 L homeolog
  • G-protein coupled receptor 124
  • ADGRA2
  • Adgra2
  • adgra2.L
  • adgra2
  • LOC616111
Reaktivität
Human, Maus, Ratte (Rattus)
72
33
26
1
Wirt
Kaninchen
72
Klonalität
Polyklonal
Konjugat
Dieser GPR124 Antikörper ist konjugiert mit Cy5
3
2
2
2
2
2
2
2
1
1
1
1
1
1
Applikation
Immunofluorescence (Paraffin-embedded Sections) (IF (p))
25
25
23
21
13
5
3
2
1
Optionen
Immunogen KLH conjugated synthetic peptide derived from human G protein coupled receptor 124
Isotyp IgG
Reinigung Purified by Protein A.
Plasmids, Primers & others Plasmide, Primers & weitere GPR124 products on genomics-online (e.g. as negative or positive controls)
Antigen
Andere Bezeichnung Gpr124/Tem5 (GPR124 Antibody Abstract)
Hintergrund

Tumor endothelial markers (TEMs) are abundantly expressed in the blood vessels of human solid tumors during angiogenesis and neoangiogensis. These include TEM1 (endosialin), TEM5 (G-protein coupled receptor 124) and TEM7 (plexin domain containing 1). TEMs are associated with the cell surface membrane at low levels in normal human and mouse tissues. TEM5 is a seven-pass transmembrane receptor, whereas TEM1, TEM7 and TEM8 span the membrane once. TEM5 expression is elevated during tumor angiogenesis and neoangiogenesis. TEM7 is highly expressed in tumor endothelium and neurons. Therefore, TEM5 and TEM7 may be suitable targets for the development of antiangiogenic therapies.

Subcellular location: Extracellular

Synonyms: DKFZp434C211, DKFZp434J0911, FLJ14390, G protein coupled receptor 124, G-protein coupled receptor 124, GP124_HUMAN, GPR 124, GPR124, KIAA1531, TEM 5, TEM5, Tumor endothelial marker 5, Tumor endothelial marker 5 precursor, GPCR GPR124.

Gen-ID 25960
Applikations-hinweise IF(IHC-P) 1:50-200
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Lagerung 4 °C
Informationen zur Lagerung Store at 4°C
Haltbarkeit 12 months
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