CYP26A1 Antikörper (Cytochrome P450, Family 26, Subfamily A, Polypeptide 1) (Cy5)

Details for Product anti-CYP26A1 Antibody No. ABIN1704841
Antigen
  • CP26
  • CYP26
  • P450RAI
  • P450RAI1
  • Cyp26
  • P450RA
  • RAH
  • RACE
  • XCYP26A1
  • cyp26
  • xCYP26
  • cp26
  • p450rai
  • p450rai1
  • CYP26A
  • cb24
  • id:ibd5061
  • wu:fb81e05
  • cytochrome P450 family 26 subfamily A member 1
  • cytochrome P450, family 26, subfamily a, polypeptide 1
  • cytochrome P450 family 26 subfamily A member 1 S homeolog
  • cytochrome P450 family 26 subfamily A member 1 L homeolog
  • cytochrome P450, family 26, subfamily A, polypeptide 1
  • CYP26A1
  • Cyp26a1
  • cyp26a1.S
  • cyp26a1.L
  • cyp26a1
Reaktivität
Human, Maus, Ratte (Rattus)
90
45
43
3
3
Wirt
Kaninchen
71
12
10
Klonalität
Polyklonal
Konjugat
Dieser CYP26A1 Antikörper ist konjugiert mit Cy5
3
3
3
3
3
3
2
1
1
1
1
1
1
1
Applikation
Immunofluorescence (Paraffin-embedded Sections) (IF (p))
57
31
18
15
12
11
10
7
6
5
2
1
1
Optionen
Immunogen KLH conjugated synthetic peptide derived from human CYP26A1
Isotyp IgG
Reinigung Purified by Protein A.
Plasmids, Primers & others Plasmide, Primers & weitere CYP26A1 products on genomics-online (e.g. as negative or positive controls)
Antigen
Andere Bezeichnung Cyp26a1 (CYP26A1 Antibody Abstract)
Hintergrund

The cytochrome P450 proteins (CYPs) are monooxygenases that catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids, and other lipids. P450 enzymes are classified into subfamilies based on their sequence similarities. CYP26A1 is a major retinoic acid catabolic enzyme. CYP26A1 plays an important role in protecting tailbud tissues from inappropriate exposure to retinoic acid. CYP26A1 transcription is epigenetically regulated by nuclear retinoic acid receptor â^2. Mutations in the gene encoding for CYP26A1 are associated with caudal agenesis and spina bifida, imperforate anus, agenesis of the caudal portions of the digestive and urogenital tracts, and malformed lumbosacral skeletal elements. CYP26A1 is upregulated in adenomatous polyposis coli mouse adenomas, human FAP adenomas, human sporadic colon carcinomas, and in the intestine of adenomatous polyposis coli (apcmcr) mutant zebrafish embryos.

Synonyms: CP26, CP26A_HUMAN, CYP26, CYP26A 1, cyp26a1, Cytochrome P450 26A1, Cytochrome P450 family 26 subfamily A polypeptide 1, Cytochrome P450 retinoic acid-inactivating 1, cytochrome P450, family 26, subfamily A, polypeptide 1, cytochrome P450, subfamily XXVIA, polypeptide 1, Cytochrome P450RAI, hP450RAI, OTTHUMP00000020102, OTTHUMP00000020103, P450, P450 retinoic acid inactivating 1, P450RAI, P450RAI1, Retinoic acid 4 hydroxylase, Retinoic acid 4-hydroxylase, Retinoic acid metabolizing cytochrome, Retinoic acid-metabolizing cytochrome.

Gen-ID 1592
Pathways Retinoic Acid Receptor Signaling Pathway, Monocarboxylic Acid Catabolic Process
Applikations-hinweise IF(IHC-P) 1:50-200
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Lagerung 4 °C
Informationen zur Lagerung Store at 4°C
Haltbarkeit 12 months
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