Chromosome 1 Open Reading Frame 124 (C1orf124) Antikörper (Cy5)

Details zu Produkt Nr. ABIN1704795
Antigen
  • Spartan
  • c1orf124
  • C1orf124
  • DDDL1880
  • DVC1
  • PRO4323
  • dJ876B10.3
  • C28H1orf124
  • SprT-like N-terminal domain
  • sprtn
  • SPRTN
Reaktivität
Human, Maus, Ratte (Rattus)
40
17
17
1
1
1
1
1
1
Wirt
Kaninchen
39
1
Klonalität
Polyklonal
Konjugat
Cy5
3
2
2
2
2
2
2
2
1
1
1
1
1
1
Applikation
Immunofluorescence (Paraffin-embedded Sections) (IF (p))
18
12
4
3
1
Optionen
Immunogen KLH conjugated synthetic peptide derived from human C1orf124
Isotyp IgG
Reinigung Purified by Protein A.
Antigen
Andere Bezeichnung C1orf124
Hintergrund

Chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8 % of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1. A breakpoint has been identified in 1q which disrupts the DISC1 gene and is linked to schizophrenia. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma. The C1orf124 gene product has been provisionally designated C1orf124 pending further characterization.

Synonyms: C1orf124, CA124_HUMAN, Chromosome 1 open reading frame 124, DDDL1880, dJ876B10.3, PRO4323, RP5-876B10.3, Zinc finger RAD18 domain-containing protein C1orf124.

Gen-ID 83932
Applikations-hinweise IF(IHC-P) 1:50-200
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Lagerung 4 °C
Informationen zur Lagerung Store at 4°C
Haltbarkeit 12 months
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