Manic Fringe Antikörper (MFNG) (Cy5)

Details for Product anti-MFNG Antibody No. ABIN1704517
Antigen
  • AW546563
  • MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
  • MFNG
  • Mfng
Reaktivität
Human, Maus, Ratte (Rattus)
57
32
32
6
6
5
5
5
3
2
2
2
1
1
Wirt
Kaninchen
50
9
2
Klonalität
Polyklonal
Konjugat
Dieser Manic Fringe Antikörper ist konjugiert mit Cy5
2
2
2
2
2
2
1
1
1
1
1
1
1
1
Applikation
Immunofluorescence (Paraffin-embedded Sections) (IF (p))
42
16
12
8
5
4
4
3
1
Optionen
Immunogen KLH conjugated synthetic peptide derived from human Manic Fringe/MFNG
Isotyp IgG
Reinigung Purified by Protein A.
Antigen
Andere Bezeichnung Manic Fringe/Mfng (MFNG Antibody Abstract)
Hintergrund

Three mammalian fringe family members, Manic, Radical and Lunatic Fringe, have been identified as proteins related to Drosophila fringe, a protein involved in development. Fringe proteins act upstream of the Notch signaling pathway and are involved in boundary determination during segmentation. Each mammalian fringe displays different patterns of expression, though all are expressed in the mouse embryo as well as in many adult tissues. Radical fringe plays a key role in the development of the limb bud. Lunatic fringe is required for normal somite segmentation and patterning and is thought to be a target of the molecular clock. Manic fringe, also involved in somatic development, has been shown to render mouse NIH/3T3 cells tumorigenic in SCID mice.

Synonyms: 3-N-acetylglucosaminyltransferase manic fringe, Beta-1, Beta-1,3-N-acetylglucosaminyltransferase manic fringe, MFNG, MFNG_HUMAN, O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase.

Gen-ID 4242
Pathways Notch Signalweg
Applikations-hinweise IF(IHC-P) 1:50-200
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Lagerung 4 °C
Informationen zur Lagerung Store at 4°C
Haltbarkeit 12 months
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