ARID3A Antikörper (AA 201-300) (Cy5)

Produktnummer ABIN1704424

Produktdetails anti-ARID3A Antikörper (Cy5)

Target: ARID3A (AT Rich Interactive Domain 3A (BRIGHT-Like) (ARID3A))

Bindungsspezifität: AA 201-300

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ARID3A Antikörper ist konjugiert mit Cy5

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Homologie: Human,Mouse,Rat,Cow,Sheep,Pig,Horse,Chicken

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human DRIL1/ARID3A

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu ARID3A

Target: ARID3A (AT Rich Interactive Domain 3A (BRIGHT-Like) (ARID3A))

Andere Bezeichnung: DRIL1/ARID3A (ARID3A Produkte)

Synonyme: ARID3A antikoerper, dril1 antikoerper, dril3 antikoerper, bright antikoerper, e2fbp1 antikoerper, BRIGHT antikoerper, DRIL1 antikoerper, DRIL3 antikoerper, E2FBP1 antikoerper, Dril1 antikoerper, Bright antikoerper, Dri1 antikoerper, AT-rich interaction domain 3A antikoerper, AT-rich interaction domain 3A S homeolog antikoerper, AT rich interactive domain 3A (BRIGHT-like) antikoerper, AT rich interactive domain 3C (BRIGHT-like) antikoerper, ARID3A antikoerper, arid3a antikoerper, Arid3a antikoerper, arid3a.S antikoerper, arid3c antikoerper

Hintergrund:

Synonyms: ARI3A_HUMAN, ARID domain-containing protein 3A, ARID3A, AT rich interactive domain-containing protein 3A, AT-rich interactive domain-containing protein 3A, B cell regulator of IgH transcription, B-cell regulator of IgH transcription, Bright, dead ringer like 1, Dead ringer-like protein 1, DRIL1, DRIL3, E2F binding protein 1, E2F-binding protein 1, E2FBP1.

Background: ARID3A, also known as DRIL1 in humans and Bright (for B cell regulator of IgH transcription) in mice, are the mammalian homologs of the Drosophila Dri (dead ringer) protein. ARID3A is developmentally regulated and is expressed in a restricted set of cells, including differentiating cells of the gut and salivary glands. ARID3A represents a member of a unique family of transcriptional activators that shares sequence similarity to proteins of SWI/SNF complexes, it contains an A/T-rich DNA-binding (ARID) domain and a distinct domain involved in tetramerization. The gene encoding ARID3A is linked to a marker of Peutz-Jeghers syndrome, which is an autosomal-dominant disorder characterized by melanocytic macules of the lips, multiple gastrointestinal hamartomatous polyps and an increased risk for various neoplasms, including gastrointestinal cancer. E2FBP1 (E2F-1 binding protein 1) is identical to ARID3A in the carboxy terminal region. E2FBP1 appears to lack DNA binding and transactivation domains, and it functions to regulate the transcription of proteins involved in cell proliferation by binding to the transcription factor E2F-1.

Gen-ID: 1820

Pathways: Chromatin Binding