ARID3A Antikörper (AT Rich Interactive Domain 3A (BRIGHT-Like)) (Cy5)

Details for Product anti-ARID3A Antibody No. ABIN1704424
Antigen
  • ARID3A
  • dril1
  • dril3
  • bright
  • e2fbp1
  • BRIGHT
  • DRIL1
  • DRIL3
  • E2FBP1
  • Dril1
  • Bright
  • Dri1
  • AT-rich interaction domain 3A
  • AT-rich interaction domain 3A S homeolog
  • AT rich interactive domain 3A (BRIGHT-like)
  • AT rich interactive domain 3C (BRIGHT-like)
  • ARID3A
  • arid3a
  • Arid3a
  • arid3a.S
  • arid3c
Reaktivität
Human, Maus, Ratte (Rattus)
69
32
30
4
4
3
2
2
2
1
1
1
Wirt
Kaninchen
52
17
Klonalität
Polyklonal
Konjugat
Dieser ARID3A Antikörper ist konjugiert mit Cy5
2
2
2
1
1
1
1
1
1
1
1
1
1
Applikation
Immunofluorescence (Paraffin-embedded Sections) (IF (p))
53
23
21
20
12
11
8
3
2
1
1
1
Optionen
Immunogen KLH conjugated synthetic peptide derived from human DRIL1/ARID3A
Isotyp IgG
Reinigung Purified by Protein A.
Plasmids, Primers & others Plasmide, Primers & weitere ARID3A products on genomics-online (e.g. as negative or positive controls)
Antigen
Andere Bezeichnung Dril1/Arid3a (ARID3A Antibody Abstract)
Hintergrund

ARID3A, also known as DRIL1 in humans and Bright (for B cell regulator of IgH transcription) in mice, are the mammalian homologs of the Drosophila Dri (dead ringer) protein. ARID3A is developmentally regulated and is expressed in a restricted set of cells, including differentiating cells of the gut and salivary glands. ARID3A represents a member of a unique family of transcriptional activators that shares sequence similarity to proteins of SWI/SNF complexes, it contains an A/T-rich DNA-binding (ARID) domain and a distinct domain involved in tetramerization. The gene encoding ARID3A is linked to a marker of Peutz-Jeghers syndrome, which is an autosomal-dominant disorder characterized by melanocytic macules of the lips, multiple gastrointestinal hamartomatous polyps and an increased risk for various neoplasms, including gastrointestinal cancer. E2FBP1 (E2F-1 binding protein 1) is identical to ARID3A in the carboxy terminal region. E2FBP1 appears to lack DNA binding and transactivation domains, and it functions to regulate the transcription of proteins involved in cell proliferation by binding to the transcription factor E2F-1.

Synonyms: ARI3A_HUMAN, ARID domain-containing protein 3A, ARID3A, AT rich interactive domain-containing protein 3A, AT-rich interactive domain-containing protein 3A, B cell regulator of IgH transcription, B-cell regulator of IgH transcription, Bright, dead ringer like 1, Dead ringer-like protein 1, DRIL1, DRIL3, E2F binding protein 1, E2F-binding protein 1, E2FBP1.

Gen-ID 1820
Pathways Chromatin Binding
Applikations-hinweise IF(IHC-P) 1:50-200
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Lagerung 4 °C
Informationen zur Lagerung Store at 4°C
Haltbarkeit 12 months
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