FMR1 Antikörper (Fragile X Mental Retardation 1) (AA 480-530) (Cy5)

Details for Product anti-FMR1 Antibody No. ABIN1704395
Antigen
  • AT24755
  • BcDNA:GM08679
  • CG6203
  • Dmel\\CG6203
  • EP(3)3517
  • FMR
  • FMR1
  • FMRP
  • FMRp
  • FXR
  • Fmrp
  • cg6203
  • dFMR
  • dFMR1
  • dFMRP
  • dFXR
  • dFXR1
  • dFXRP
  • dFmr1
  • dFmrp
  • dfmr
  • dfmr1
  • dfxr
  • dfxr1
  • dmfr1
  • fmr
  • fmr1
  • FRAXA
  • POF
  • POF1
  • zFMR1
  • Fmr-1
  • CG6203 gene product from transcript CG6203-RC
  • fragile X mental retardation 1
  • fragile X mental retardation syndrome 1
  • Fmr1
  • FMR1
  • fmr1
Epitop
AA 480-530, pSer500
22
16
14
13
12
9
7
5
3
2
1
1
1
1
1
1
Reaktivität
Human, Maus, Ratte (Rattus)
150
80
79
9
8
4
4
3
3
2
2
1
1
1
Wirt
Kaninchen
100
42
14
Klonalität
Polyklonal
Konjugat
Dieser FMR1 Antikörper ist konjugiert mit Cy5
8
5
5
4
4
4
4
4
4
4
4
3
1
1
1
1
1
Applikation
Immunofluorescence (Paraffin-embedded Sections) (IF (p))
123
69
53
31
21
13
11
10
7
5
4
3
2
2
2
1
Optionen
Immunogen KLH conjugated synthetic phosphopeptide derived from human FMRP around the phosphorylation site of Ser500
Isotyp IgG
Reinigung Purified by Protein A.
Plasmids, Primers & others Plasmide, Primers & weitere FMR1 products on genomics-online (e.g. as negative or positive controls)
Antigen
Andere Bezeichnung Fmrp (FMR1 Antibody Abstract)
Hintergrund

Translation repressor. Component of the CYFIP1-EIF4E-FMR1 complex which binds to the mRNA cap and mediates translational repression. In the CYFIP1-EIF4E-FMR1 complex this subunit mediates translation repression (By similarity). RNA-binding protein that plays a role in intracellular RNA transport and in the regulation of translation of target mRNAs. Associated with polysomes. May play a role in the transport of mRNA from the nucleus to the cytoplasm. Binds strongly to poly(G), binds moderately to poly(U) but shows very little binding to poly(A) or poly(C).

Subcellular location: Cytoplasm, Nucleus

Synonyms: POF, FMRP, POF1, FRAXA, Fragile X mental retardation protein 1, Protein FMR-1, FMR1

Gen-ID 2332
UniProt Q06787
Pathways Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
Applikations-hinweise IF(IHC-P) 1:50-200
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Lagerung 4 °C
Informationen zur Lagerung Store at 4°C
Haltbarkeit 12 months
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