NIPBL Antikörper (Nipped-B Homolog (Drosophila)) (Cy5)

Details for Product anti-NIPBL Antibody No. ABIN1704324
Antigen
  • CDLS
  • CDLS1
  • IDN3
  • IDN3-B
  • Scc2
  • SCC2W
  • scc2
  • nipbl
  • scc2-2
  • NIPBL
  • nipbla
  • wu:fi33d08
  • 4921518A06Rik
  • 4933421G18Rik
  • C79399
  • Idn3
  • NIPBL, cohesin loading factor
  • Nipped-B homolog-like
  • NIPBL, cohesin loading factor S homeolog
  • nipped-B homolog b (Drosophila)
  • nipped-B-like protein A
  • Nipped-B homolog (Drosophila)
  • NIPBL
  • NIPBLL
  • nipbl.S
  • LOC427439
  • nipblb
  • LOC100164947
  • nipbl
  • Nipbl
Reaktivität
Human, Maus, Ratte (Rattus)
44
40
20
4
3
1
1
1
1
1
Wirt
Kaninchen
24
19
11
2
Klonalität
Polyklonal
Konjugat
Dieser NIPBL Antikörper ist konjugiert mit Cy5
3
3
3
1
1
1
1
1
1
1
1
1
1
1
1
1
Applikation
Immunofluorescence (Paraffin-embedded Sections) (IF (p))
28
27
16
12
11
11
9
3
3
2
1
Optionen
Immunogen KLH conjugated synthetic peptide derived from human IDN3
Isotyp IgG
Reinigung Purified by Protein A.
Plasmids, Primers & others Plasmide, Primers & weitere NIPBL products on genomics-online (e.g. as negative or positive controls)
Antigen
Andere Bezeichnung Idn3 (NIPBL Antibody Abstract)
Hintergrund

This gene encodes the homolog of the Drosophila melanogaster Nipped-B gene product and fungal Scc2-type sister chromatid cohesion proteins. The Drosophila protein facilitates enhancer-promoter communication of remote enhancers and plays a role in developmental regulation. It is also homologous to a family of chromosomal adherins with broad roles in sister chromatid cohesion, chromosome condensation, and DNA repair. The human protein has a bipartite nuclear targeting sequence and a putative HEAT repeat. Condensins, cohesins and other complexes with chromosome-related functions also contain HEAT repeats. Mutations in this gene result in Cornelia de Lange syndrome, a disorder characterized by dysmorphic facial features, growth delay, limb reduction defects, and mental retardation. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

Synonyms: CDLS, Colon tumor susceptibility 2, Delangin, DKFZp434L1319, FLJ11203, FLJ12597, FLJ13354, FLJ13648, FLJ44854, IDN 3, IDN 3 protein, IDN 3 protein isoform A, IDN 3 protein isoform B, IDN 3B, IDN3 B, IDN3 protein, IDN3 protein isoform A, IDN3 protein isoform B, IDN3B, Mis 4, Mis4, Nipbl, NIPBL_HUMAN, Nipped B homolog Drosophila, Nipped B homolog, Nipped B like, Nipped B like protein, Nipped-B-like protein, Scc 2, SCC 2 homolog, Scc2, SCC2 homolog, Sister chromatid cohesion protein Mis4.

Pathways Sensory Perception of Sound, Stem Cell Maintenance
Applikations-hinweise IF(IHC-P) 1:50-200
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Lagerung 4 °C
Informationen zur Lagerung Store at 4°C
Haltbarkeit 12 months
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