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Cofilin Antikörper (pSer24) (Cy5)

CFL1 Reaktivität: Ratte IF (cc), IF (p) Wirt: Kaninchen Polyclonal Cy5
Produktnummer ABIN1704204
  • Target Alle Cofilin (CFL1) Antikörper anzeigen
    Cofilin (CFL1) (Cofilin 1 (CFL1))
    Bindungsspezifität
    • 18
    • 17
    • 16
    • 14
    • 11
    • 8
    • 7
    • 7
    • 7
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer24
    Reaktivität
    • 132
    • 93
    • 89
    • 5
    • 5
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    Ratte
    Wirt
    • 136
    • 9
    • 2
    Kaninchen
    Klonalität
    • 136
    • 10
    Polyklonal
    Konjugat
    • 71
    • 10
    • 10
    • 7
    • 6
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Cofilin Antikörper ist konjugiert mit Cy5
    Applikation
    • 71
    • 61
    • 44
    • 42
    • 40
    • 40
    • 30
    • 26
    • 16
    • 12
    • 7
    • 7
    • 3
    • 3
    • 3
    • 2
    • 2
    Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Kreuzreaktivität
    Ratte
    Homologie
    Human,Mouse,Dog,Cow,Pig,Chicken,Guinea Pig
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic phosphopeptide derived from human CFL1/CFL2 around the phosphorylation site of Ser24
    Isotyp
    IgG
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  • Applikationshinweise
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    Cofilin (CFL1) (Cofilin 1 (CFL1))
    Andere Bezeichnung
    Cofilin (CFL1 Produkte)
    Hintergrund

    Synonyms: Cofilin/CFL1 Ser24, 18 kDa phosphoprotein, CFL 1, CFL, CFL1, Cofilin 1, Cofilin 1 non muscle, Cofilin non muscle isoform, p18, COF1_HUMAN.

    Background: The protein encoded by this gene can polymerize and depolymerize F-actin and G-actin in a pH -dependent manner. Increased phosphorylation of this protein by LIM kinase aids in Rho-induced reorganization of the actin cytoskeleton. Cofilin is a widely distributed intracellular actin-modulating protein that binds and depolymerizes filamentous F-actin and inhibits the polymerization of monomeric G-actin in a pH -dependent manner. It is involved in the translocation of actin-cofilin complex from cytoplasm to nucleus.

    Gen-ID
    1072
    Pathways
    Regulation of Cell Size, Tube Formation, Protein targeting to Nucleus, CXCR4-mediated Signaling Events
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