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CDON Antikörper (AA 101-200) (Alexa Fluor 350)

CDON Reaktivität: Human IF (cc), IF (p) Wirt: Kaninchen Polyclonal Alexa Fluor 350
Produktnummer ABIN1693740
$438.15
Zzgl. Versandkosten $45.00
100 μL
Lieferung in 11 bis 16 Werktagen
  • Target Alle CDON Antikörper anzeigen
    CDON (Cell Adhesion Molecule-Related/down-Regulated By Oncogenes (CDON))
    Bindungsspezifität
    • 14
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 101-200
    Reaktivität
    • 37
    • 2
    • 1
    • 1
    • 1
    Human
    Wirt
    • 26
    • 7
    • 4
    • 1
    Kaninchen
    Klonalität
    • 35
    • 3
    Polyklonal
    Konjugat
    • 13
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CDON Antikörper ist konjugiert mit Alexa Fluor 350
    Applikation
    • 19
    • 12
    • 12
    • 8
    • 4
    • 4
    • 3
    • 1
    Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Homologie
    Human,Mouse,Rat,Dog,Cow,Sheep,Rabbit
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human CDON
    Isotyp
    IgG
  • Applikationshinweise
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C/-80 °C
    Informationen zur Lagerung
    Store at -20°C, for long storage, store at -80°C. Avoid multiple freeze-thaw cycles
    Haltbarkeit
    12 months
  • Target
    CDON (Cell Adhesion Molecule-Related/down-Regulated By Oncogenes (CDON))
    Andere Bezeichnung
    CDON (CDON Produkte)
    Synonyme
    CDO, CDON1, HPE11, ORCAM, Cdo, Cd0, Orcam, cb507, wu:fa10c03, wu:fb94b11, zgc:158240, cdon-A, cell adhesion associated, oncogene regulated, cell adhesion molecule-related/down-regulated by oncogenes, cell adhesion associated, oncogene regulated L homeolog, CDON, Cdon, cdon, cdon.L
    Hintergrund

    Cell adhesion molecule-related/down-regulated by oncogenes (CDO) and BOC (brother of CDO) are members of the immunoglobulin/fibronectin type III repeat family and act as cell surface receptors. CDO is a component of a cell-surface receptor complex which also contains BOC, NEO1, CTNNB1 and cadherins and which acts as a mediator of cell-cell interactions between muscle cells. CDO and BOC are single pass membrane proteins that play a role in myogenic cell differentiation. Together, CDO and BOC participate in a positive feedback loop with MyoD, a myogenic transcription factor. The 1,242 amino acid rat CDO protein has a 24 residue signal sequence, five Ig V-like repeats, a 25 residue membrane-spanning region, three FNIII-like repeats and a cytoplasmic region of 256 amino acids containing a proline-rich stretch. The human protein contains 1,225 amino acid residues and shares significant homology with the domain structures of the rat protein.

    Subcellular location: Cell membrane

    Synonyms: CDO, CDON, Cell adhesion molecule-related/down-regulated by oncogenes, CDON_HUMAN.

    Gen-ID
    50937
    Pathways
    Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Embryonic Body Morphogenesis
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