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Inversin Antikörper (AA 31-130) (Alexa Fluor 350)

INVS Reaktivität: Human, Maus IF (cc), IF (p) Wirt: Kaninchen Polyclonal Alexa Fluor 350
Produktnummer ABIN1693617
$438.15
Zzgl. Versandkosten $45.00
100 μL
Lieferung in 4 bis 6 Werktagen
  • Target Alle Inversin (INVS) Antikörper anzeigen
    Inversin (INVS)
    Bindungsspezifität
    • 14
    • 5
    • 1
    • 1
    AA 31-130
    Reaktivität
    • 22
    • 16
    • 2
    Human, Maus
    Wirt
    • 21
    • 1
    Kaninchen
    Klonalität
    • 22
    Polyklonal
    Konjugat
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Inversin Antikörper ist konjugiert mit Alexa Fluor 350
    Applikation
    • 12
    • 12
    • 7
    • 7
    • 3
    • 3
    • 2
    • 2
    • 1
    Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Homologie
    Rat,Cow,Sheep,Chimpanzee
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human Inversin
    Isotyp
    IgG
  • Applikationshinweise
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C/-80 °C
    Informationen zur Lagerung
    Store at -20°C, for long storage, store at -80°C. Avoid multiple freeze-thaw cycles
    Haltbarkeit
    12 months
  • Target
    Inversin (INVS)
    Andere Bezeichnung
    Inversin (INVS Produkte)
    Synonyme
    invs-a, INVS, MGC140477, inv, NPH2, NPHP2, INV, Nphp2, RGD1563359, wu:fe47e11, inversin S homeolog, inversin, Inversin, invs.S, INVS, Bm1_38710, PTRG_09181, EAMY_RS33690, LOAG_11716, invs, Invs
    Hintergrund

    Nephrocystin-2 is a 1,065 amino acid protein that exists as three alternatively spliced isoforms and is essential for establishment of the left-right axis and normal renal development. Localizing to the cytoplasm, cytoskeleton, membrane and nucleus, nephrocystin-2 is expressed during presomite-stage embryos and persists in adulthood, with high levels of expression in liver and kidney. Mice expressing nephrocystin-2 mutations are primarily generated by random insertional mutagenesis and result in the reversal of left/right polarity and cyst formation in the kidneys. Furthermore, altered nephrocystin-2 function reverses nodal and lefty expression, indicating that nephrocystin-2 signaling occurs upstream of these proteins involved in the development of asymmetry.

    Subcellular location: Cytoplasm, Cell membrane

    Synonyms: INV, Inversion of embryo turning homolog, inversion of embryonic turning, INVS, Nephrocystin 2, Nephrocystin-2, Nephrocystin2, nephronophthisis 2 infantile, NPH2, NPHP2, INVS_HUMAN.

    Gen-ID
    27130
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