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BTBD14A Antikörper (AA 401-500) (Alexa Fluor 350)

BTBD14A Reaktivität: Human IF (cc), IF (p) Wirt: Kaninchen Polyclonal Alexa Fluor 350
Produktnummer ABIN1693272
$438.15
Zzgl. Versandkosten $45.00
100 μL
Lieferung in 11 bis 16 Werktagen
  • Target Alle BTBD14A Antikörper anzeigen
    BTBD14A (BTB (POZ) Domain Containing 14A (BTBD14A))
    Bindungsspezifität
    • 14
    • 11
    • 9
    • 8
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 401-500
    Reaktivität
    • 39
    • 6
    • 5
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    Human
    Wirt
    • 38
    • 1
    Kaninchen
    Klonalität
    • 39
    Polyklonal
    Konjugat
    • 14
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser BTBD14A Antikörper ist konjugiert mit Alexa Fluor 350
    Applikation
    • 25
    • 17
    • 12
    • 12
    • 4
    • 3
    • 3
    • 1
    • 1
    Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Homologie
    Human,Mouse,Rat,Dog,Cow,Sheep,Horse,Chicken
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human BTBD14A
    Isotyp
    IgG
  • Applikationshinweise
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C/-80 °C
    Informationen zur Lagerung
    Store at -20°C, for long storage, store at -80°C. Avoid multiple freeze-thaw cycles
    Haltbarkeit
    12 months
  • Target
    BTBD14A (BTB (POZ) Domain Containing 14A (BTBD14A))
    Andere Bezeichnung
    BTBD14A (BTBD14A Produkte)
    Synonyme
    NACC2, BTBD14A, BEND9, BTBD14, BTBD31, Btbd14a, 0610020I02Rik, AI448087, C030048H19Rik, NACC family member 2, nucleus accumbens-associated protein 2-like, nucleus accumbens associated 2, BEN and BTB (POZ) domain containing, NACC2, LOC100354269, Nacc2
    Hintergrund

    BTBD14A is a 587 amino acid protein that contains one BTB/POZ domain. The BTB/POZ domain mediates homomeric and heteromeric POZ-POZ interactions and is common to transcriptional regulators involved in chromatin modeling. In several BTB/POZ containing proteins, including BCL-6 and the promyelocytic leukemia zinc-finger (PLZF) oncoprotein, this domain interacts with the SMRT/N-CoR-mSin3A HDAC complex and is directly involved in repressing and silencing gene transcription. When this domain is deleted, as with the oncogenic PLZF-RAR chimera of promyelocytic leukemias, this transcriptional repression is attenuated. This suggests that BTBD14A may play a role in transcription regulation.

    Subcellular location: Nucleus

    Synonyms: BTB POZ domain containing 14A, BTB domain containing 14A, BTB/POZ domain containing protein 14A, BTB/POZ domain-containing protein 14A, BTBD 14A, BTBD14, NAC-2, NACC2, NACC2_HUMAN, Nucleus accumbens-associated protein 2.

    Gen-ID
    54813
    Pathways
    Positive Regulation of Response to DNA Damage Stimulus
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