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HDAC1 Antikörper (Histone Deacetylase 1) AA 466-482 Primary Antibody

HDAC1 Reaktivität: Human IHC, ELISA, WB Wirt: Kaninchen Polyclonal unconjugated
Pubmed (3 references)
Produktnummer ABIN129652
$658.50
Zzgl. Versandkosten $45.00 und $20.00 Trockeneis
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Lieferung in 1 bis 2 Werktagen
  • Target Alle HDAC1 Antikörper anzeigen
    HDAC1
    Bindungsspezifität
    • 26
    • 17
    • 16
    • 15
    • 13
    • 13
    • 9
    • 8
    • 8
    • 8
    • 7
    • 7
    • 6
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 466-482
    Reaktivität
    • 184
    • 94
    • 72
    • 9
    • 8
    • 8
    • 7
    • 6
    • 6
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    Human
    Wirt
    • 153
    • 32
    • 8
    Kaninchen
    Klonalität
    • 162
    • 31
    Polyklonal
    Konjugat
    • 113
    • 14
    • 12
    • 11
    • 7
    • 7
    • 7
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    Dieser HDAC1 Antikörper ist unkonjugiert
    Applikation
    • 152
    • 115
    • 49
    • 45
    • 32
    • 25
    • 17
    • 14
    • 10
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
    Produktmerkmale
    Concentration Definition: by UV absorbance at 280 nm
    Immunogen
    Anti-HDAC-1 antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to amino acids 466-482 of Human HDAC-1.
    Isotyp
    IgG
  • Applikationshinweise
    Anti-HDAC-1 Antibody has been tested for use in ELISA, immunohistochemistry and western blot.  Specific conditions for reactivity should be optimized by the end user.   Specific nuclear staining is observed by IHC.  Expect bands at 65 kDa in size corresponding to HDAC-1 by western blotting in the appropriate cell lysate or extract.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1.33 mg/mL
    Buffer
    0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
  • Scharer, Barwick, Guo, Bally, Boss: "Plasma cell differentiation is controlled by multiple cell division-coupled epigenetic programs." in: Nature communications, Vol. 9, Issue 1, pp. 1698, (2018) (PubMed).

    Nohata, Hanazawa, Kinoshita, Inamine, Kikkawa, Itesako, Yoshino, Enokida, Nakagawa, Okamoto, Seki: "Tumour-suppressive microRNA-874 contributes to cell proliferation through targeting of histone deacetylase 1 in head and neck squamous cell carcinoma." in: British journal of cancer, Vol. 108, Issue 8, pp. 1648-58, (2013) (PubMed).

    Unoki, Nishidate, Nakamura: "ICBP90, an E2F-1 target, recruits HDAC1 and binds to methyl-CpG through its SRA domain." in: Oncogene, Vol. 23, Issue 46, pp. 7601-10, (2004) (PubMed).

  • Target
    HDAC1
    Andere Bezeichnung
    HDAC-1 (HDAC1 Produkte)
    Synonyme
    GON-10, HD1, RPD3, RPD3L1, CG7471, DHDAC1, DRpd3, DmHDAC1, Dmel\\CG7471, E(var)3-64BC, HDAC, HDAC-1, HDAC1, Hdac1, Rpd3/HDAC, Su(var)3-26, Su(var)326, Su(var)328, dHDAC-1, dHDAC1, dRPD3, dRpd3, dmHDA401, drpd3, hdac1, l(3)04556, l(3)64Cc, rpd3, rpd[3], gon-10, hdac1b, rpd3l1, Rpd3, GB14706, hdac1-b, chunp6919, hdac-1, mp:zf637-2-001987, wu:fb19h11, wu:fi06f03, zgc:101582, zgc:65818, Hdac1-ps, MommeD5, ARABIDOPSIS HISTONE DEACETYLASE 1, ARABIDOPSIS HISTONE DEACETYLASE 19, ATHD1, ATHDA19, ATRPD3A, F20D10.250, F20D10_250, HDA1, HDA19, HISTONE DEACETYLASE, HISTONE DEACETYLASE 19, HISTONE DEACETYLASE19, RPD3A, histone deacetylase 1, HDM, ab21, hdac1a, histone deacetylase 1, Histone deacetylase 1, histone deacetylase, histone deacetylase 1 S homeolog, histone deacetylase Rpd3, histone deacetylase 1 L homeolog, HDAC1, hdac1.S, LOC411503, hdac1, Hdac1, HD1, hda-1, hdac1.L, LOC748850
    Hintergrund
    HDAC-1 antibody recognizes HDAC1 (also known as HD1, histone deacetylase 1, RPD3, RPD3L1) which belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, it deacetylates p53 and modulates its effect on cell growth and apoptosis.
    Synonyms: GON 10 antibody, HD 1 antibody, hdac1: histone deacetylase 1 antibody, Histone deacetylase 1 (HD1) antibody, Histone deacetylase 1 antibody, RPD3 (reduced potassium dependency yeast homolog) like 1 antibody
    Gen-ID
    3065, 13128860
    UniProt
    Q13547
    Pathways
    Neurotrophin Signalübertragung, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Mitotic G1-G1/S Phases, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Negative Regulation of intrinsic apoptotic Signaling, Embryonic Body Morphogenesis
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