RECK Antikörper (AA 621-832)

Produktnummer ABIN1108847

Produktdetails anti-RECK Antikörper

Target: RECK (Reversion-Inducing-Cysteine-Rich Protein with Kazal Motifs (RECK))

Bindungsspezifität: AA 621-832

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser RECK Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Spezifität: This antibody reacts with RECK.

Kreuzreaktivität (Details): Species reactivity (tested):Human

Aufreinigung: Protein A agarose

Immunogen: Recombinant RECK protein (621-832 a.a)

Klon: 32C10A

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS containing 50 % glycerol, pH 7.2. No preservative is contained.

Konservierungsmittel: Without preservative

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Store (in aliquots) at -20 °C.

Details zu RECK

Target: RECK (Reversion-Inducing-Cysteine-Rich Protein with Kazal Motifs (RECK))

Andere Bezeichnung: RECK / ST15 (RECK Produkte)

Hintergrund: A membrane-anchored glycoprotein, RECK is encoded by a RECK gene (reversion-inducing cysteine-rich protein with Kazal motifs) identified as a transformation suppressor gene. This 110 kDa protein consists of 971a.a. The protein contains protease inhibitor like domains such as the Kazal motif, and epidermal growth factor (EGF) like repeats. Takahashi et al. reported that restoration pf RECK expression in malignant cells resulted in suppression of invasive activity with a concomitant decrease in the secretion of matrix metalloproteinase-9 (MMP-9), a key enzyme involved in tumor invasion and metastasis.Synonyms: Reversion-inducing cysteine-rich protein with Kazal motifs, Suppressor of tumorigenicity 15 protein

Gen-ID: 8434

NCBI Accession: NP_066934

UniProt: O95980