serine/arginine-Rich Splicing Factor 3 Proteine (SRSF3)

The protein encoded by SRSF3 is a member of the serine/arginine (SR)-rich family of pre-mRNA splicing factors, which constitute part of the spliceosome. Zusätzlich bieten wir Ihnen SRSF3 Antikörper (68) und SRSF3 Kits (8) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
SRSF3 6428 P84103
SRSF3 20383 P84104
Ratte SRSF3 SRSF3 361814  
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Showing 4 out of 5 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 50 Days
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 50 Days
Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 11 bis 12 Tage
Hefe Rind (Kuh) His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage

SRSF3 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human ,
Mouse (Murine)

Am meisten referenzierte SRSF3 Proteine

  1. Human SRSF3 Protein expressed in Wheat germ - ABIN1319754 : Walsh, Suchanek, Cyphert, Kohan, Szeszel-Fedorowicz, Salati: Serine arginine splicing factor 3 is involved in enhanced splicing of glucose-6-phosphate dehydrogenase RNA in response to nutrients and hormones in liver. in The Journal of biological chemistry 2013 (PubMed)
    Show all 2 Pubmed References

Weitere Proteine zu serine/arginine-Rich Splicing Factor 3 (SRSF3) Interaktionspartnern

Human serine/arginine-Rich Splicing Factor 3 (SRSF3) Interaktionspartner

  1. Results show that SRSF3 impairs the autoregulation mechanism of SRSF5 and promotes the overexpression of SRSF5 in oral squamous cell carcinoma.

  2. TDP43 alters most splicing events with splicing factor SRSF3 in triple-negative breast cancer.

  3. Loss of SRSF3 expression was significantly associated with poor survival and shorter disease-free survival, particularly in early stages, in colorectal cancer.

  4. Findings reveal the molecular mechanism of SRSF3 in pri-miRNA processing and support the previously proposed explanation for the highly conserved position of CNNC in SRSF3-enhanced pri-miRNA processing.

  5. High expression of SRSF3 is associated with oral squamous cell carcinoma.

  6. RBM4-SRSF3-MAP4K4 constitutes a novel mechanism for manipulating the metastasis of colorectal cancer cells through the JNK1 signaling pathway.

  7. MicroRNA-1908-5p contributes to the oncogenic function of the splicing factor SRSF3 via NKIRAS2 axis in osteosarcoma cells.

  8. Dehydroepiandrosterone (DHEA) and cortisol modulate SRSF9 and SRSF3 in a different way and data suggest that the anti-glucocorticoid effect of DHEA, among other mechanisms, is also exerted by modulating the expression of proteins involved in the splicing of the GR pre-mRNA.

  9. that SRSF3 controls the expression of the miR-132/212 cluster through regulating REST expression

  10. Alternative splicing of U2AF1 reveals a shared repression mechanism for duplicated exons controlled by SRF3.

  11. Introduction of point mutations in the SRSF3-binding site or knockdown of SRSF3 expression in cells reduces human papillomavirus 18 929;3434 splicing and E1;E4 production but activates other, minor 929;3465 and 929;3506 splicing. Knockdown of SRSF3 expression also enhances the expression of E2 and L1 mRNAs.

  12. data indicate that the Human Papillomavirus E2 protein links the viral replication cycle to epithelial differentiation via SRSF3, a key cellular regulator of high-risk (HR)-HPV gene expression

  13. Results suggested that SRSF3 is associated with the initiation and development of OSCC and may be a biomarker and therapeutic target of OSCC.

  14. we also demonstrated frequent co-overexpression and positive correlation of DARPP-32, SRp20 and CD44E expression levels in human gastric primary tumors.

  15. PTBP1 and PTBP2 impaired autoregulation of SRSF3 in oral squamous cell carcinoma cancer cells.

  16. Results show that YTHDC1 promotes exon inclusion in targeted mRNAs through recruiting pre-mRNA splicing factor SRSF3 while blocking SRSF10 mRNA binding.

  17. These data indicate that SRSF3 affects a global change of gene expression to maintain cell homeostasis.

  18. We propose that SRSF3 could act as a coordinator of the expression of PDCD4 protein via two mechanisms on two alternatively spliced mRNA isoforms.

  19. This new function of SRSF3 not only explains why overexpression of SRSF3 is required for ovarian cancer cell growth and survival but also offers a new insight into the mechanism of the neoplastic transformation.

  20. SRSF3 and hnRNP H1 are the first splicing factors identified which regulate the production of these functionally distinct HER2 splice variants and therefore maybe important for the regulation of HER2 signaling.

SRSF3 Protein Überblick

Protein Überblick

The protein encoded by this gene is a member of the serine/arginine (SR)-rich family of pre-mRNA splicing factors, which constitute part of the spliceosome. Each of these factors contains an RNA recognition motif (RRM) for binding RNA and an RS domain for binding other proteins. The RS domain is rich in serine and arginine residues and facilitates interaction between different SR splicing factors. In addition to being critical for mRNA splicing, the SR proteins have also been shown to be involved in mRNA export from the nucleus and in translation. Two transcript variants, one protein-coding and the other non-coding, have been found for this gene.

Genbezeichner und Symbole assoziert mit SRSF3

  • serine and arginine rich splicing factor 3 (SRSF3)
  • serine/arginine-rich splicing factor 3 (Srsf3)
  • serine/arginine-rich splicing factor 3 S homeolog (srsf3.S)
  • serine and arginine rich splicing factor 3 (Srsf3)
  • serine/arginine-rich splicing factor 3a (srsf3a)
  • AL024116 Protein
  • sfrs3 Protein
  • si:zc263a23.9 Protein
  • SRP20 Protein
  • X16 Protein
  • zgc:86626 Protein

Bezeichner auf Proteinebene für SRSF3

pre-mRNA-splicing factor SRP20 , splicing factor, arginine/serine-rich 3 , splicing factor, arginine/serine-rich, 20-kD , splicing factor, arginine/serine-rich 3 (SRp20) , splicing factor, arginine serine-rich 3 , splicing factor, arginine/serine-rich 3a

6428 Homo sapiens
20383 Mus musculus
380152 Xenopus laevis
419815 Gallus gallus
403687 Canis lupus familiaris
540276 Bos taurus
361814 Rattus norvegicus
368925 Danio rerio
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